University of Groningen
Birth and death of cellular senescence Wang, Boshi
DOI:
10.33612/diss.131223530
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Publication date: 2020
Link to publication in University of Groningen/UMCG research database
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Wang, B. (2020). Birth and death of cellular senescence. University of Groningen. https://doi.org/10.33612/diss.131223530
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Curriculum Vitae
135
Boshi Wang
EDUCATION
• Doctor of Philosophy (OIO) (Feb 2016 — Sep 2020):
ERIBA, University Medical Center Groningen (UMCG), University of Groningen, Groningen, The Netherlands. (Supervisor: Dr. Marco Demaria)
Thesis Title: The birth and death of cellular senescence. • Master of Philosophy (Sep 2012 — Dec 2015): (Research Postgraduate & Research Assistant II)
Department of Biochemistry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. (Supervisor: Dr. Mai Har Sham)
Thesis Title: The roles of Irx3/5 genes and Hedgehog signaling in mammalian cochlear development.
• Bachelor of Science (Sep 2008 — Jun 2012):
School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China. (Supervisor: Prof. Weiliang Xia)
Cumulative Average Mark: 86.42/100; Cumulative Overall GPA: 3.67/4.00. (Top 10)
Thesis Title: A study on the regulation of multi-drug resistance in cancer cells by Sirtuin proteins.
PROFESSIONAL GRANTS & AWARDS
• Jan Kornelis De Cock-Stichting Research Grant (Feb 2017; €4,000 EUR).
• JSDB Travel Fellowship (47th Annual Meeting of JSDB. Feb 2014; ¥100,000 JPY).
List of Publication
136
1. Wang, B., Brandenburg, S., Hernandez-Segura, A., Vliet, T., Jongbloed, E., Wilting, S., Ohtani, N., Jager, A. & Demaria, M. CDK4/6 inhibition promotes senescent states with restricted secretory phenotype and reduced toxicity. Biorxiv 2020.06.05.135715 (2020). doi:10.1101/2020.06.05.135715 (under review)
2. Wang, B., Kohli, J. & Demaria, M. Senescent Cells in Cancer Therapy: Friends or Foes?
Trends Cancer (2020). doi:10.1016/j.trecan.2020.05.004
3. Fontana, L., Mitchell, S., Wang, B., Tosti, V., Vliet, T., Veronese, N., Bertozzi, B., Early, D., Maissan, P., Speakman, J. & Demaria, M. The effects of graded caloric restriction: XII. Comparison of mouse to human impact on cellular senescence in the colon. Aging Cell 17, e12746 (2018).
4. Demaria, M., O’Leary, M., Chang, J., Shao, L., Liu, S., Alimirah, F., Koenig, K., Le, C., Mitin, N., Deal, A., Alston, S., Academia, E., Kilmarx, S., Valdovinos, A., Wang, B., Bruin, A., Kennedy, B., Melov, S., Zhou, D., Sharpless, N., Muss, H. & Campisi, J. Cellular
Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse. Cancer Discov 7, 165–176 (2017).
5. Liu, Y., Xie, Q., Wang, B., Shao, J., Zhang, T., Liu, T., Huang, G. & Xia, W. Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics.
Protein Cell 4, 702–710 (2013).
6. Xie, Q., Liu, Y., Shao, J., Yang, J., Liu, T., Zhang, T., Wang, B., Mruk, D., Silvestrini, B., Cheng, C. & Xia, W. Male contraceptive Adjudin is a potential anti-cancer drug. Biochem
Pharmacol 85, 345–355 (2013).
7. Shao, J., Liu, T., Xie, Q., Zhang, T., Yu, H., Wang, B., Ying, W., Mruk, D., Silvestrini, B., Cheng, C. & Xia, W. Adjudin attenuates lipopolysaccharide (LPS)- and ischemia-induced microglial activation. J Neuroimmunol 254, 83–90 (2013).
