University of Groningen
Structural and biochemical characterization of Roco proteins Terheyden, Susanne
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Publication date: 2018
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Terheyden, S. (2018). Structural and biochemical characterization of Roco proteins. University of Groningen.
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Chapter 3
A homologue of the Parkinson’s disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover
Egon Deyaert, Lina Wauters, Giambattista Guaitoli, Albert Konijnenberg, Margaux Leemans, Susanne Terheyden, Arsen Petrovic, Rodrigo Gallardo, Henderikus Pots, Peter J.M. Van Haastert, Frank Sobott, Johannes Gloeckner, Rouslan Efremov, Arjan Kortholt, Wim Versées
This chapter has been published in: Nat. Commun. 2017, 8, 1008.
ED, LW, PV, AP, RE, JG, FS, AK and WV designed the experiments. ED, GG, ML, HP and ST purified the proteins. LW and RE performed EM analysis. ED and RG performed the SEC-MALS analysis. ED and WV performed the SEC-SAXS analysis. ST, AP and ED performed the AUC analysis. AK and ED performed the native MS analysis. ED performed the kinetic and FRET experiments. ED and WV wrote the manuscript. All the authors read and edited the manuscript.
Supplementary Information
