University of Groningen
On the molecular biology of telomeres Stinus Ruiz de Gauna, Sonia
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date: 2018
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Stinus Ruiz de Gauna, S. (2018). On the molecular biology of telomeres: Lessons from budding yeast. University of Groningen.
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
Stellingen
Behorende bij het proefschrift
On the molecular biology of telomeres Lessons from budding yeast
Sonia Stinus Ruiz de Gauna, 3 December 2018
1. A threshold of about 40 nt of telomeric sequence establishes the boundary between telomeres and DSBs. (This thesis) 2. We provide evidence that Pif1 inhibits telomerase activity in vivo
at DNA ends regardless of telomere sequence length. (This thesis)
3. S. cerevisiae telomeric G-quadruplexes, although they protect the chromosome ends when the classical capping mechanisms are absent or impaired, are not essential for cell viability. (This thesis)
4. The fact that cells harbouring Rap1-free tlc1-tm telomeres are fit implies that the essential function of Rap1 is not its telomeric function. (This thesis)
5. It's not because things are difficult that we dare not venture. It's because we dare not venture that they are difficult. (Seneca) 6. Le rire est la distance la plus courte entre deux personnes.
(Victor Borge)
7. La vida es fascinante: sólo hay que mirarla a través de las gafas correctas. (Alejandro Dumas)
