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Sphingolipids in essential hypertension and endothelial dysfunction
Spijkers, L.J.A.
Publication date
2013
Link to publication
Citation for published version (APA):
Spijkers, L. J. A. (2013). Sphingolipids in essential hypertension and endothelial dysfunction.
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Contents
Chapter 1. General introduction 9
Chapter 2. Sphingolipids and the orchestration of endothelium-derived 41 vasoactive factors: When endothelial function demands
greasing
Aim of the study 59
Chapter 3. Hypertension is associated with marked alterations in 61 sphingolipid biology: A potential role for ceramide
Chapter 4. Antihypertensive treatment differentially affects vascular 93 sphingolipid biology in spontaneously hypertensive rats
Chapter 5. FTY720 (Fingolimod) increases vascular tone and blood 113 pressure in spontaneously hypertensive rats via inhibition of
sphingosine kinase
Chapter 6: The association between blood pressure and 131 glucosylceramides in spontaneously hypertensive rats
Chapter 7. Hypertension-associated alterations in sphingolipid biology 151 modulates vascular endothelin-1 signalling
Chapter 8. Calcium-dependent regulation of endothelial Weibel-Palade 169 body exocytosis via sphingosine-1-phosphate receptor 1 and 3
Chapter 9. General discussion 187
Summary 197
Nederlandstalige samenvatting 203
Supporting information 209
Dankwoord 219
About the author 224
