University of Groningen
Endocarditis
Gomes, Anna
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Publication date:
2018
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Gomes, A. (2018). Endocarditis: Improving the chain of care. University of Groningen.
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Stellingen behorende bij het proefschrift
“Endocarditis, improving the chain of care”
Anna Gomes
1. Despite great progress in medicine in general, endocarditis remains a devastating disease with high morbidity and mortality rates [This thesis, chapter 1]
2. Improvement of the outcome of patients with endocarditis, asks for optimization of the total medical chain of care [This thesis, chapters 1 and 12]
3. Structured multidisciplinary collaboration between medical specialities is key in the management of endocarditis [This thesis, chapters 1, 10 and 12]
4. An algorithm implementing non-invasive imaging techniques in addition to echocardiography improves the accuracy for diagnosing endocarditis [This thesis, chapters 2-6]
5. FDG-PET/CT should be considered in all patients with a clinical suspicion of endocarditis, as it provides important information about the presence of endocarditis and extracardiac complications [This thesis, chapter 2-6]
6. Sonication of heart valves proves to be useful in endocarditis by increasing the identification of bacteria and enabling antibiotic susceptibility testing [This thesis, chapter 7]
7. Better gentamicin blood concentrations are achieved in patients with endocarditis if the intensive care population pharmacokinetic model, with an increased volume of distribution, is used for dose calculation [This thesis, chapter 8]
8. Stentless bioprosthesis allows for radical and standardized surgical therapy with complete debridement in case of challenging active aortic valve endocarditis complicated by paravalvular abscess formation [This thesis, chapter 9]
9. Bacteria-targeted imaging is an appealing future option to accurately diagnose endocarditis early. The optimal tracer and modality needs to be further clarified [This thesis, chapter 11] 10. If we don’t get lost, we will never find the route [Kosn Littlewood]
11. Be together, not the same [Android campaign]
12. If you want to go fast, go alone. If you want to go far, go together [African proverb, from the movie “The good lie”]
