University of Groningen Endocarditis Gomes, Anna

University of Groningen

Endocarditis

Gomes, Anna

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Publication date:

2018

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Gomes, A. (2018). Endocarditis: Improving the chain of care. University of Groningen.

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Endocarditis

improving the chain of care

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ISBN:

978-94-034-0547-6 (Printed book)

978-94-034-0546-9 (Digital)

Cover design:

Jaap Gomes and Maaike van Dijk, based on sketches of Jet Gomes

Design/Lay-out:

Wendy Bour-van Telgen, Ipskamp Printing Enschede

Print:

Ipskamp Printing, Enschede

© Anna Gomes, 2018

All rights are reserved. No part of this book may be reproduced, distributed, stored in a retrieval system, or transmitted in any form or by any means, without prior written permission of the author.

Endocarditis

Improving the chain of care

Proefschrift

ter verkrijging van de graad van doctor aan de

Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. E. Sterken

en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op

maandag 4 juni 2018 om 16:15 uur

door

Anna Gomes

geboren op 7 juni 1987

te Amsterdam

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Endocarditis

Improving the chain of care

Proefschrift

ter verkrijging van de graad van doctor aan de

Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. E. Sterken

en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op

maandag 4 juni 2018 om 16:15 uur

door

Anna Gomes

geboren op 7 juni 1987

te Amsterdam

517227-L-bw-gomes

517227-L-bw-gomes

517227-L-bw-gomes

517227-L-bw-gomes

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Paranimfen

Ieneke van der Gun

René Vlielander

The work presented in this thesis was performed at the Department of Medical Microbiology of the University of Groningen and the University Medical Center Groningen. It was partly funded by the innovation fund of the Department of Medical Microbiology and by the INTERREG VA project EurHealth-1Health (202085), which is part of a Dutch-German cross-border network supported by the European Union, the Dutch Ministry of Health, Welfare and Sport (VWS), the Ministry of Economy, Innovation, Digitalisation and Energy of the German Federal State of North Rhine-Westphalia and the German Federal State of Lower Saxony.

Financial support for printing this thesis was kindly provided by the Groningen University Institute for Drug Exploration (GUIDE) of the Graduate School for Medical Sciences (GSMS), the University of Groningen, the University Medical Center Groningen, INTERREG project EurHealth-1Health, and Hermes Medical Solutions. Financial support by the Dutch Heart Foundation for the publication of this thesis is also gratefully acknowledged.

Promotor

Prof. dr. B.N.M. Sinha

Copromotores

Dr. P.P. van Geel

Dr. A.W.J.M. Glaudemans

Dr. S. van Assen

Beoordelingscommissie

Prof. dr. J.W.M. van der Meer

Prof. dr. R.A.J.O. Dierckx

Prof. dr. J.E. Degener

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Paranimfen

Ieneke van der Gun

René Vlielander

The work presented in this thesis was performed at the Department of Medical Microbiology of the University of Groningen and the University Medical Center Groningen. It was partly funded by the innovation fund of the Department of Medical Microbiology and by the INTERREG VA project EurHealth-1Health (202085), which is part of a Dutch-German cross-border network supported by the European Union, the Dutch Ministry of Health, Welfare and Sport (VWS), the Ministry of Economy, Innovation, Digitalisation and Energy of the German Federal State of North Rhine-Westphalia and the German Federal State of Lower Saxony.

Financial support for printing this thesis was kindly provided by the Groningen University Institute for Drug Exploration (GUIDE) of the Graduate School for Medical Sciences (GSMS), the University of Groningen, the University Medical Center Groningen, INTERREG project EurHealth-1Health, and Hermes Medical Solutions. Financial support by the Dutch Heart Foundation for the publication of this thesis is also gratefully acknowledged.

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Table of contents

Chapter 1

General introduction

Chapter 2

Diagnostic value of imaging in infective endocarditis: a systematic review

Chapter 3

Imaging of infective endocarditis and cardiac device infection: prospective

evaluation of a diagnostic flowchart and diagnostic accuracy of involved

imaging modalities

Chapter 4

Improving the diagnostic performance of

18

_{F-FDG PET/CT in prosthetic heart}

valve endocarditis

Chapter 5

18

_{F-FDG PET/CT in the diagnostic workup of infective endocarditis and}

related intracardiac prosthetic material: a clear message

Chapter 6

18

_{F-FDG PET/CT with clinical impact in infective endocarditis}

Chapter 7

Sonication of heart valves detects more bacteria in infective endocarditis

Chapter 8

Pharmacokinetic modeling of gentamicin in treatment of infective

endocarditis: model development and validation of existing models

Chapter 9

A standardized approach to treat complex aortic valve endocarditis:

a case series

Chapter 10

The Endocarditis Team

Chapter 11

Preclinical studies and prospective clinical applications for bacteria-targeted

imaging: the future is bright

Chapter 12

Summary, discussion and conclusion

Chapter 13

Nederlandse samenvatting

Chapter 14

List of abbreviations

Chapter 15

Dankwoord

Chapter 16

Curriculum vitae

8

32

62

90

116

124

134

156

172

190

204

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242

254

264

270

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