University of Groningen
Developmental and pathological roles of BMP/follistatin-like 1 in the lung
Tania, Navessa
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Publication date: 2017
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Tania, N. (2017). Developmental and pathological roles of BMP/follistatin-like 1 in the lung. University of Groningen.
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Developmental and Pathological Roles of BMP/Follistatin-like 1 in the Lung
1. Endothelial Fstl1 is required for postnatal lung development by modulating BMP/Smad signaling (this thesis).
2. A history of smoking causes a long-lasting increase of Fstl1 in the lungs (this thesis).
3. Blocking Fstl1 in airway epithelium is a strategy worth pursuing to reduce airway inflammation in COPD (this thesis).
4. Restoring proper BMP activation in airway epithelium of COPD patients could inhibit goblet cell metaplasia, basal cell hyperplasia and reverse loss of (variant) club cells (this thesis).
5. A tightly controlled regulation is required for organ development. On the contrary, a high degree of freedom is required for personal development.
6. Breathing in smoke early in life could take your breath away later in life.
7. Surviving in a new environment is about using the resources that are available, not about looking for those that are absent.
8. The fun part about research is generating a creative strategy to discover something new, not merely the moment of the discovery itself.
9. Stepping back and getting lost are the prices to be paid to move forward and discover the unknown.
10. Asking the right questions is more important than having the right answers (modified from Jiddu Krishnamurti).
Navessa P. Tania Groningen 2017
