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Diagnostic aspects of human alphaherpesvirus infections in dermato-venerology - Contents

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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

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Diagnostic aspects of human alphaherpesvirus infections in dermato-venerology

Folkers, E.

Publication date

1999

Link to publication

Citation for published version (APA):

Folkers, E. (1999). Diagnostic aspects of human alphaherpesvirus infections in

dermato-venerology.

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Contents

Chapter 1 General introduction

page 9

1.1 Herpesviruses, important to mankind 9

1.2 Role of human herpesvirus infections in dermato-venereology 10

1.3 Microbiology of herpetic infection 16 1.4 Methodology for diagnosing herpetic infections 17

1.5 Aim and outline of this thesis 2 5

C h a p t e r 2 Tzanck smear a n d viral culture in diagnosis of herpes 33 simplex virus a n d varicella-zoster virus infection

2.1 A rapid diagnostic test (Tzanck test) to exclude herpesvirus infections 35 in vesicles, blisters and pustules

2.2 Diagnostic value of Tzanck smear in herpetic and non-herpetic 41 vesicular and bullous skin disorders in pediatric practice

2.3 Tzanck smear in diagnosing genital herpes 51 2.4 Diagnosis and treatment of pustular disorders in the neonate 63

Chapter 3 Immunogold electron microscopy in diagnosis of herpes 87

simplex virus and varicella-zoster virus infection

3.1 The use of colloidal gold immunoelectron microscopy to diagnose 89 varicella-zoster virus (VZV) infections by rapid discrimination

between VZV, HSV-1 and HSV-2

3.2 Improved detection of HSV by electron microscopy in clinical 107 specimens using ultracentrifugation and colloidal gold

immuno-electron microscopy: comparison with viral culture and cytodiagnosis

3.3 Rapid diagnosis in varicella and herpes zoster: re-evaluation of 125 direct smear (Tzanck test) and electron microscopy including

colloidal gold immuno-electron microscopy in comparison with virus isolation

3.4 Immunoelectron microscopy for rapid diagnosis of varicella-zoster 137 virus in a complicated case of human T-Cell lymphotropic virus

type 1 infection

Addendum Addendum to chapter 3. 1 4 7

A simple storage system for EM grids. Quality management in complicated EM studies for research and routine diagnosis

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Chapter 4 Detection of varicella-zoster virus and herpes 151

simplex virus by polymerase chain reaction with

degenerated primers

Chapter 5 Immune response to varicella-zoster virus infection 169

in vivo: immunoglobulins, complement and

cellular infiltrates

Chapter 6 Summary & Samenvatting 185

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