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University of Groningen

Perfect pitstops

Loeffen, Erik

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from

it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date:

2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Loeffen, E. (2019). Perfect pitstops: Towards evidence-based supportive care in children with cancer.

Rijksuniversiteit Groningen.

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Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

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PROPOSITIONS

1. Guidelines that have not included patient representatives during development, lack a critical angle to be comprehensive in daily practice. – This thesis

2. As individual clinicians have the time nor the multi-angled knowledge that guideline development panels have, these panels should go to great lengths to formulate recommendations to guide clinical care even when high-quality evidence is scarce. – This thesis

3. With the current high survival rates in children with cancer, the question how cure is achieved has become nearly as important as the question if cure is achieved. – This thesis

4. If there is no plan for implementation and monitoring of effect prior to guideline development, one should save themselves the effort to develop a guideline. - This thesis

5. Not the success of the procedure, but the comfort of the child should be the main focus in painful procedures. – This thesis

6. Exploring treatments with a decreased intensity without compromising anti-tumor efficacy are critical to further improve survival in children with cancer. – This thesis

7. When guidelines are referred to as “cookbook medicine”, one should see a recommendation as an ingredient rather than a recipe. – This thesis 8. A thesis is but the mere product of a PhD project, becoming a good

scientist is the goal.

9. Je kan niet opruimen zonder eerst een bende te maken.

10. “It’s better to create something that others criticise than to create noth-ing and criticise others.” – Ricky Gervais

11. “Because in a split second, it’s gone.” – Ayrton Senna

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