University of Groningen
Porphyromonas gingivalis, the beast with two heads
Gabarrini, Giorgio
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Publication date: 2018
Link to publication in University of Groningen/UMCG research database
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Gabarrini, G. (2018). Porphyromonas gingivalis, the beast with two heads: A bacterial role in the etiology of rheumatoid arthritis. University of Groningen.
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Propositions accompanying the thesis
Porphyromonas gingivalis, the beast with two heads – A bacterial role in the etiology of rheumatoid arthritis –
1. “High quality science is so beautiful” – Laura Marcela Palma Medina
2. The members of the microbiome have countless, often unexpected, effects on our health (Chapter 2)
3. The key to the success of P. gingivalis in its oral niche is hidden in its proteome (Chapter 3)
4. The Porphyromonas peptidylarginine deiminase (PPAD) is a constant fixture of P. gingivalis (Chapter 4)
5. There’s no place like OM (Chapter 5)
6. Conservation of PPAD crosses the species boundaries (Chapter 6)
7. PPAD anchorage to the outer membrane can be hampered by structural mutations (Chapter 7)
8. If it looks like PPAD, acts like PPAD, and sorts like PPAD, then probably it’s PPAD 9. “People are like proteomics, whatever you look for, you’ll find” – Suruchi Nepal
10. “Sometimes science is more art than science, Morty. A lot of people don’t get that” – Rick Sanchez
11. Deeper knowledge of the complex interactions between P. gingivalis and the human immune system might just be the key to unlock the secrets of the etiopathogenesis of rheumatoid arthritis
