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Magnetic resonance imaging in neonatal hypoxic-ischemic brain injury Liauw, L.

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Liauw, L.

Citation

Liauw, L. (2009, March 19). Magnetic resonance imaging in neonatal hypoxic-ischemic brain injury. Retrieved from

https://hdl.handle.net/1887/13690

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/13690

Note: To cite this publication please use the final published version (if

applicable).

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MAGNETIC RESONANCE IMAGING IN

NEONATAL HYPOXIC-ISCHEMIC BRAIN INJURY

Lishya Liauw

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MAGNETIC RESONANCE IMAGING IN NEONATAL HYPOXIC-ISCHEMIC BRAIN

INJURY

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden,

op gezag van Rector Magnificus Prof. Mr. P.F. van der Heijden, volgens besluit van het College voor Promoties

te verdedigen op donderdag 19 maart 2009 klokke 16.15 uur

door

Lishya Liauw

geboren te Bandung (Indonesie)

in 1964

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Promotor Prof. Dr. M.A. van Buchem

Co-promotores Dr. J. van der Grond Dr. G. van Wezel-Meijler

Referent Dr. R.J. Vermeulen (VU Medisch Centrum Amsterdam)

Overige leden Prof. Dr. H.A. Delemarre-van de Waal

Prof. Dr. J.W.H. Leer (Radboud Universiteit Nijmegen Medisch Centrum)

Prof. Dr. F.J. Walther

© 2009 L Liauw

All rights preserved. No parts of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without prior written permission of the author.

ISBN 978-90-9023426-7

Cover photograph: ‘Nijmegen sunrise’ by Lishya Liauw Printed by Druno en Dekker drukkers, Noordwijkerhout

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Que le Soleil est beau quand tout frais il se lève, Comme une explosion nous lançant son bonjour ! Bienheureux celui-là qui peut avec amour Saluer son coucher plus glorieux qu’un rêve !

Le coucher du soleil romantique (Les fleurs du mal) Charles Baudelaire

To my parents and grand-parents

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CONTENTS

Chapter 1 Introduction and aims 9

Chapter 2 Hypoxic-ischemic encephalopathy: diagnostic value of conventional MR imaging pulse sequences in term-born neonates

17

Chapter 3 Differentiating normal myelination from hypoxic- ischemic encephalopathy on T1-weighted MR images:

a new approach

33

Chapter 4 Differentiation between peritrigonal terminal zones and hypoxic-ischemic white matter injury on MRI

47

Chapter 5 Is there a way to predict outcome in (near) term neonates with hypoxic-ischemic encephalopathy based on MR imaging?

61

Chapter 6 Do Apparent Diffusion Coefficient measurements predict outcome in children with neonatal hypoxic-ischemic encephalopathy?

75

Chapter 7 Prediction of short-term neurological outcome in full- term neonates with hypoxic-ischaemic encephalopathy based on combined use of electroencephalogram and neuro-imaging

91

Chapter 8 Comparing brain white matter on sequential cranial ultrasound and MRI in very preterm infants

111

Chapter 9 Summary and conclusions References in alphabetical order

Summary in Dutch (samenvatting in het Nederlands) Curriculum vitae

List of publications

131 140 149 155 156

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