University of Groningen
Bioconjugation of metal-based compounds for targeted biomedical applications: from drug
delivery to mass spectrometry imaging
Han, Jiaying
DOI:
10.33612/diss.113122575
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Publication date: 2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Han, J. (2020). Bioconjugation of metal-based compounds for targeted biomedical applications: from drug delivery to mass spectrometry imaging. University of Groningen. https://doi.org/10.33612/diss.113122575
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Propositions
1. In general, an important challenge in cancer treatment is to find a technology for targeted delivery and controlled release of anti-cancer drugs to eradicate tumor cells while sparing normal ones. (This thesis)
2. Supramolecular metallacages offer new opportunities to develop targeted drug delivery systems by modifying the ligand structure through pre- and post-self-assembly. (This thesis, Chapter 2 and 3) 3. Photocleavable (PC) mass-tags allow matrix-free targeted imaging of proteins in tissue sections. This strategy exhibits a high potential to improve sensitivity and spatial resolution, and allow a high degree of multiplexing. (This thesis, Chapter 6)
4. Never give up easily, even if the research develops in an unexpected direction. This may be another window that God opened for us, and we name it Plan B. (This thesis)
5. Reading thousands of books is not as good as traveling thousands of miles, the same is true for research. (experienced by the PhD candidate)
6. Never forget why you started, and your mission can be accomplished. —不忘初心,方得始终。(experienced by the PhD candidate)
7. Don't be ashamed to ask questions, you will learn from the answer.(experienced by the PhD candidate)
8. I am prepared for the worst, but hope for the best. — Benjamin Disraeli.
9. You have to believe in yourself. That’s the secret of success. — Charles Chaplin.
10. A mother’s voice is the most beautiful sound in the world. — Dante Alighieri.