University of Groningen
Management of heavy menstrual bleeding
van den Brink, Marian
DOI:
10.33612/diss.160486947
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Publication date: 2021
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van den Brink, M. (2021). Management of heavy menstrual bleeding: Towards a patient-centred approach. University of Groningen. https://doi.org/10.33612/diss.160486947
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Management of heavy menstrual bleeding
Towards a patient-centred approach
Cover & Lay-out: Iris Gruppen
Printing: Ridderprint, the Netherlands
Part of the research described in this thesis is financially supported by the Netherlands Organisation for Health and Development (ZonMw) and is gratefully acknowledged.
Financial support for the publication of this thesis, provided by Research Institute SHARE (School of HeAlth REsearch), University of Groningen, University Medical Centre Groningen (UMCG) and SBOH, employer of GP trainees, is gratefully acknowledged.
© Copyright M.J. van den Brink, 2021
Cover & Lay-out: Iris Gruppen
Printing: Ridderprint, the Netherlands
Part of the research described in this thesis is financially supported by the Netherlands Organisation for Health and Development (ZonMw) and is gratefully acknowledged.
Financial support for the publication of this thesis, provided by Research Institute SHARE (School of HeAlth REsearch), University of Groningen, University Medical Centre Groningen (UMCG) and SBOH, employer of GP trainees, is gratefully acknowledged.
© Copyright M.J. van den Brink, 2021
All rights reserved. No part of this thesis may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, without the written permission of the author or, when appropriate, of the publishers of the publications.
Management of heavy menstrual
bleeding
Towards a patient-centred approach
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op maandag 15 maart 2021 om 14:30 uur
door
Maaike Johanna van den Brink
geboren op 8 augustus 1985 te Opsterland
PPrroommoottoorreess
Prof. Dr. M.Y. Berger Prof. Dr. M.Y. Bongers
CCoopprroommoottoorr Dr. J.H. Dekker
BBeeoooorrddeelliinnggssccoommmmiissssiiee Prof. Dr. W.J.J. Assendelft Prof. Dr. M.J.E. Mourits
PPrroommoottoorreess
Prof. Dr. M.Y. Berger Prof. Dr. M.Y. Bongers
CCoopprroommoottoorr Dr. J.H. Dekker
BBeeoooorrddeelliinnggssccoommmmiissssiiee Prof. Dr. W.J.J. Assendelft Prof. Dr. M.J.E. Mourits
Chapter 1 General introduction
Chapter 2 Incidence and treatment of heavy menstrual bleeding in general practice
Chapter 3 Levonorgestrel-releasing intrauterine system (Mirena) versus endometrial ablation (Novasure) in women with heavy menstrual bleeding: a multicentre randomised controlled trial (Study protocol)
Chapter 4 Levonorgestrel-releasing intrauterine system versus endometrial ablation for heavy menstrual bleeding
Chapter 5 The levonorgestrel intrauterine system versus endometrial ablation for heavy menstrual bleeding: a cost-effectiveness analysis
Chapter 6 Women’s preferences for the levonorgestrel intrauterine system versus endometrial ablation for heavy menstrual bleeding
Chapter 7 Effect of lower von Willebrand factor and factor XI levels on levonorgestrel intrauterine system and endometrial ablation treatment success in heavy menstrual bleeding
– an explorative study
Chapter 8 Factors affecting patient recruitment to trials: qualitative research in general practice
Chapter 9 Summary and general discussion Nederlandse samenvatting Dankwoord
About the author
Research Institute SHARE
Contents 9 23 45 59 99 123 145 161 183 211 221 227 229