• No results found

Hydrogel based drug carriers for controlled release of hydrophobic drugs and proteins

N/A
N/A
Protected

Academic year: 2021

Share "Hydrogel based drug carriers for controlled release of hydrophobic drugs and proteins"

Copied!
4
0
0

Bezig met laden.... (Bekijk nu de volledige tekst)

Hele tekst

(1)

Hydrogel based drug carriers for controlled release of hydrophobic drugs and proteins

Ke, P.

Citation

Ke, P. (2011, September 14). Hydrogel based drug carriers for controlled release of hydrophobic drugs and proteins. Retrieved from https://hdl.handle.net/1887/17833

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/17833

Note: To cite this publication please use the final published version (if applicable).

(2)

106

Appendix C

Acknowledgement

(3)

107

Acknowledgement

In the end I would like to acknowledge all the people without whom this thesis would not have been possible.

My foremost thanks go to Alexander Kros, for his infinite energy which served as a constant source of inspiration throughout my whole PhD study, to Itsuro Tomatsu for many fruitful discussions, and to Johannes G.E.M. Fraaije whose advice were always result oriented and arrived just on time.

I am grateful to all my colleagues from the Soft Matter Chemistry Group. Many thanks to Edgar M. Blokhuis, Agur Sevink, Jan Raap, Hana Marsden, Ahmed Jilali, Chundong Chau, Joris Kuipers, Fabiola Porta, Frank Versluis, Marat Charlaganov, Tingting Zheng, Giuliana Martelli, Karen Sliedregt-Bol, Harshal Zope, Karol M. Langner, Martin Rabe, Yue Gao and Nestor Lopez Mora for the supports and the fun that we had together.

Jacques van der Ploeg and Wim Jesse are acknowledged for their generous technical assistance. Michelle van der Haar and Esther van Delft are acknowledged for their kind administration work. I am thankful to all the students who have contributed to my research projects including Pieter Bikker, Daan van der Es, Frithjof Godschalk, Koos Rooijers, Dave van den Helder, Yorick. P. Vogels, Michelle v.d. Slot, Dayenne van Leeuwen, Lot vd Graaf, Paul de Goede, Felix Nencu, Willem Noteborn, Jarno ter Beek and Hizel Ashti.

I especially appreciated the collaborations with Prof. Dr. H.P. Spaink, Dr. Annemarie Meijer, Chao Cui (Molecular Cell Biology, Institute Biology Leiden, the Netherlands), Dr. Leo Price, Sreenivasa Ramaiahgari (Toxicology group, Leiden/Amsterdam center for drug research, the Netherlands), Dr. A. Korobko, Ben Norder (Nanostructured materials group, TU Delft, the Netherlands), Prof. Dr. Wim Jiskoot, Christophe Barnier Quer (Drug delivery technology group, Leiden/Amsterdam center for drug research, the Netherlands), Dr. John van Noort, Bram van den Broek (Physics of life processes group, Leiden institute of physics, the Netherlands), Dr. S.A.E. Marras (New Jersey medical school, the

(4)

108

United States), Prof. Dr. Hermen Overkleeft, Prof. Dr. Gijs van der Marel, Nan Li (Bio- organic synthesis group, Leiden institute of chemistry, the Netherlands), Prof. Dr. Jan H.

van Esch, Iwona Ziemecka (Self-assembling systems group, TU Delft, the Netherlands) and Dr. M.A. Huisman (Leids universitair medisch centrum, the Netherlands) for those exciting results that have been, is being and will be generated. Prof. Dr. Johan Lugtenburg is specially acknowledged for all his good advices.

Thanks to all my friends and family for their endless patience and for always being there.

There are so many other people who helped and supported me, I’m sorry that I’m not able to list all your names here, but I am really grateful to all of you!

Referenties

GERELATEERDE DOCUMENTEN

Recently we have developed in situ forming hydrogel systems composed of maleimide modified dextran (Dex-mal) and thiol functionalized β-cyclodextrins for the

In conclusion, a light responsive hydrogel system composed of azobenzene functionalized dextran (AB–Dex) and β-cyclodextrin functionalized dextran (CD–Dex) has

The capability of protein storage and light triggered release from the obtained hydrogels were examined using green fluorescent protein (GFP) as a model protein... of fresh

In dit proefschrift wordt de bereiding en karakterisatie van in situ vormende hydrogelen - gebaseerd op biocompatibele polymeren- beschreven, die als toepassing het

Hydrogel based drug carriers for controlled release of hydrophobic drugs and proteins..

Finally, the alcohol group was activated by tosylation in a good yield (85%) to be reactive towards primary amines of the silica particles. Synthesis

In the first release experiment 5, 10 and 15 µg/mL of anti­MMP9 and anti­TNFα VHHs was added to three types of hydrogel: HA­TA, CS­TA and Dex­TA.. Anti­TrkA VHHs were

2 coverslips were coated with 0.5 mg/mL PLL-PEG, washed with HEPES 10 mM 7.4 pH twice, micropatterning them, and coating them with gelatin FITC, transferring