University of Groningen
Lanthipeptide engineering: non-canonical amino acids, click chemistry and ring shuffling
Deng, Jingjing
DOI:
10.33612/diss.112973724
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Publication date: 2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Deng, J. (2020). Lanthipeptide engineering: non-canonical amino acids, click chemistry and ring shuffling. University of Groningen. https://doi.org/10.33612/diss.112973724
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Acknowledgements
Ten years ago when I was an undergraduate, I dreamed that I could have the chance to study abroad. This dream is like a seed planted in my heart. A few years later, as you all know, I got the opportunity to do a Ph.D. in the Netherlands. And now, I have almost finished my studies in Groningen. When I look back on my Ph.D. journey, my heart is full of gratitude. It is a unique and great experience that I enjoyed and learned a lot. At this moment, I would like to take this opportunity to express my gratitude to the people who have supported me throughout my Ph.D.
First and foremost, I would like to express my sincere gratitude to my supervisor, Oscar. Thank you for offering me this opportunity to join the Molecular Genetics group. You are a wonderful supervisor and the most optimistic person I have ever known. Thank you very much for the trust, freedom, encouragement, and support that you gave to me during my Ph.D.
Secondly, I would like to thank the members of the assessment committee, Prof. dr. N. I. Martin, Prof. dr. J. G. Roelfes and Pro. dr. D. G. Moll., for reading and approving this thesis.
Also, I want to thank all my collaborators Prof. dr. S. Panke, Prof. dr. N. Budisa, Dr. S. Schmitt, and Dr. V. Kubyshkin. Thank you all for your help in my research. Prof. dr. S. Pank and Dr. S. Schmitt, I’m very honored to join the project of ring shuffling. Prof. dr. N. Budisa and Dr. V. Kubyshkin, thank you for providing the hydrophobic pentynoyl peptides.
Studying and working in MolGen has been great. I would also like to express my gratitude to my dear colleagues. Jan, Jaap and Danny, thank you for leading our group with pleasure working atmosphere together with Oscar. Siger, Anne DJ, Harma, Anne H, Manon, and Jannet, thank you for all your help and your friendly chats during
these years. Manolo, thank you for your guidance at the beginning of my Ph.D. You are such a knowledgeable person and thank you for the discussion when I got stuck in my project which really helped me a lot. Jakob, thank you for your generous help in chapter 4 and chapter 5. Chenxi, you are such an amazing person. It’s always very pleasant to talk with you. Your presence makes my life so much easier and happier. Meishan, we have only known each other for a short time, but we get close very soon. I really enjoyed shopping with you. All the best for your Ph.D. Dear Xue, thank you for taking care of me when I travelled to Lausanne. You are a lifelong friend, so I’m sure we will keep in touch. I wish you a successful career and a happy life with Chengjian and the baby.
A big thank you to my sport mates Jella, Auke, Chunxu, Zhibo and Qian. I en-joyed a lot when we play badminton together. Jella, you are an excellent teammate who never complains and always help me to win. Thank you very much. Zhibo, thank you
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A ck no w le dg eme ntsfor your generous help when I got troubles. Your smartness, diligence and passion for research will surely help you to achieve a successful research career. Qian, we have had countless scientific discussions and personal conversations. Thank you for all your suggestions. Your wisdom and fortitude are what I need to learn.
A special thanks goes to my Paranymphs. Amanda, our “Chinese” friend, you are such a nice person with a warm heart. Thank you for organizing the lady’s night. I really enjoyed it, and the food and conversations we had are precious memories for me. I’m looking forward to seeing you in China one day. Thank you for helping me with the Dutch summary. Dear Patricia, I’m very glad to be friends with you. Your enthusiasm is very impressive and inspiring. You are always there when I need you. Taking good care of yourself and I wish you all the success in your Ph.D.
I would also like to thank all other (ex-) members of MolGen for their help and friendship. Fleur, Victoria, Diego, Ruben, Claudia, Jhonatan, Eduardo, Anna, Barbara, Luiza, Anne-Marie, Maike, Marielle, Jingqi, Yuxin, Fangfang, Xinghong, Lu, Yushan, Longcheng, Yunhai, Ilaria, Tycho, Yi, Jason, Liang, Dongdong, Xin, Tonia, Lieke, Angel, Mirjam, Ard Jan, Rieza, Arnoldas, Ana, Andrius, Angel, Sjoerd, Katrin, Robin, Clement, Renske, Dimitra, Lance, and Stefano, thank you all for the discussions, suggestions and parties.
My life in Groningen would not be so pleasant without the friendship of my non-MolGeners friends. Juan, we came to Groningen together. Although we don’t meet each other very often, we are just like old friends. As you are going to marry this year, I wish you and Xiaoma all the success, happiness and joy in life. Changsen, Yingying, Liqiang and Yuanyuan, I really enjoyed the dinner and conversations we had for the last few years. Many thanks for your help, support and sharing. Lianghui, thank you very much for your delicious dinners. I have had a lot of fun to play games with you. Wenjia, Li, Jingyao and Ruixue, thank you for your warm-hearted accompany and support, especially after Yuanze went back to China. Bin Jiang, Haoqi, Huatang, Xuan, Fangying and Yuan, I had a lot of fun when we go skiing together. Thank you for bringing me these enjoyable memories. Jiaying, Jing Sun, Jing Wu, Yanan, Qihui, Yingruo, Haoxiao, Bin Han, Wei, Qi, Jielin, XiaoDong, Baojie, Ji, Peiliang, Lijuan, Peipei, Yanjun, Yizhou, Keni, Shanshan, Zhangping, Huala, Kai, Chao, Qian Wang, Bingquan, Zefeng, Bidong, Ran and Xiaochen, thank you for all the fun and your friendship.
I sincerely appreciate China Scholarship Council (CSC) for supporting my study in the Netherlands.
Special thanks to my special friends and family:
首先,我要感谢程王丽和唐建军还有我的干女儿小糖果,从来格罗宁根的 第一天你邀我们去你家吃饭,就注定了我们之间的缘分,你让我见识到了美 好的友情是什么样子,我们的关系已经远远不止是朋友,更似家人,谢谢你