Endocrine and metabolic features of familial longevity : the Leiden Longevity Study

Here, we show that compared to their partners, the offspring of familial nonagenarians displayed similar non-fasted serum levels of IGF-1, IGFBP3 and insulin but lower

In this study we related serum IGF-1 levels in nonagenarian siblings from the Leiden Longevity Study to the family mortality history score of their parents.. We

We have compared serum thyroid hormone function parameters in a group of middle-aged offspring of long-living nonagenarian siblings and a control group of their partners, all

The relation between lower family history score of the parents of the nonagenarian siblings and higher thyrotropin along with lower serum thyroxine levels in the

The purpose of this study was to investigate a mutual association between triiodothyronine and pro-inflammatory cytokines. Here, we show that higher circulating

Nonagenarians from parents who reached an exceptionally high age had higher thyrotropin levels, lower free thyroxine and lower free triiodothyronine levels when

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In chapter thirteen we will empirically test this novel method as compared to the common approach in a population of renal patients, a population known to