University of Groningen
A computational study on the nature of DNA G-quadruplex structure
Gholamjani Moghaddam, Kiana
DOI:
10.33612/diss.159767021
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from
it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date:
2021
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Gholamjani Moghaddam, K. (2021). A computational study on the nature of DNA G-quadruplex structure.
University of Groningen. https://doi.org/10.33612/diss.159767021
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
Acknowledgements
At the end of my PhD journey, I would like to thank a number of people who helped and supported me in different ways through this journey.
First and foremost, my deepest appreciation goes to my first supervisor Shirin for giving me the opportunity to do my own research project in the group. I cannot express how glad I am that I moved to Groningen and did my PhD with you. I am very grateful for the trust and freedom that you gave me during my PhD. I really appreciate your advice, effort, insightful feedback and constant support. You are always available for any questions and problems: thank you for that.
I would also like to thank my second supervisor Siewert-Jan. Thank you for giving me the opportunity to conduct a part of my PhD project in your group and helpful suggestions to all chapters.
Many thanks to Alex for helping me with CG simulations and carefully reading the thesis within a very short time that you had during your teaching. I really appreciate your effort and helpful ideas.
I am truly grateful to Prof. Hashemianzadeh for introducing me to this research topic and the time and effort in supervising me on MD simulations of G-quadruplex-ligand complexes (chapter 3 and partially chapter 4). Thanks also for allowing me to grow as an independent researcher.
Further, I express my gratitude to the members of the assessment committee, Prof. Andreas Dreuw, Prof. Anastasia Borschevsky and Prof. Ryan Chiechi for taking the time to evaluate and approve my thesis.
A special acknowledgement goes to Henriet for the cheerful help with any academic and non-academic problems.
I would like to say special thanks to Edison. It was a pleasure to share office with you. Thanks for the support and positivity at every moment. I have really enjoyed all nice discussions at work and great time that we had outside the office. I wish you and Mary the best of luck and happiness and also successful completion of your PhD thesis. I am also very happy that you accepted to be one of my paranymphs.
Special thanks to Wouter and Goran for your great works that you did during your 122
Acknowledgements 123
Master’s project. I am really happy that our team work resulted in a nice publication that is a part of this thesis. I wish you a lot of success in your future career.
Luis, thanks for the friendly times during the coffee breaks and all entertaining moments you made for the group. Siva, thank you for helping me to improve my scripts and also all nice foods especially lemon rice. Selim, thanks for the nice and helpful attitude specially at the end of my PhD. Thanks also to Mónica for translating the summary of this thesis into Dutch. Eryn, thank you for your friendly help with the proofreading of my propositions. I am grateful to Ria for the help and support particularly for accommodation when we came to Groningen. My appreciation also goes to Shirin and Anastasia for organizing nice meetings of the FSE Female Scientist Networking group.
I would also like to thank the members of the molecular dynamics group, especially Ignacio, Haleh and Maria for the great help on CG simulations.
Of course, thanks to all members of the theoretical chemistry group for all entertaining borrels, outings and Christmas parties. Also, a big thanks to current and former members of the group: Wim, Max, Albert, Kathir, Riccardo, Remco, Tomasso, Meilani, Maria, Issac, Vito, Manoy, Cees, Florian, Fernando, Helena, Kilian, Serena, I-ting . . .
Furthermore, I would like to thank my close friends in the Netherlands: Sanaz and Arman who make my life in Groningen memorable. You are truly remarkable and wonderful friends, you are like my family. I really enjoy all moments that we spend together. I have great memories from nice foods, drinks, movies, game nights and holidays together. Thank you for all fun time and emotional support. I wish both of you all the best with your future. Finally, I am extremely grateful to my parents. Thank you for always making me feel loved and protected. Thanks also to my brother and sister for your deep love, continued support and encouragement. My deepest thanks go to Armin, my beloved husband and best friend. Thank you for accompanying me through all happiest and saddest days in my life. You always inspire me with your positive attitude and give me energy, strength and constant smile. Thank you for supporting me and believing in me every step of my life with patience, kindness, great insight and love. It is hard to express my deepest gratitude to you. I am really happy to have you as one of my paranymphs. You are my everything. I love you from the bottom of my heart!