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University of Groningen A computational study on the nature of DNA G-quadruplex structure Gholamjani Moghaddam, Kiana

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University of Groningen

A computational study on the nature of DNA G-quadruplex structure

Gholamjani Moghaddam, Kiana

DOI:

10.33612/diss.159767021

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

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Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Gholamjani Moghaddam, K. (2021). A computational study on the nature of DNA G-quadruplex structure. University of Groningen. https://doi.org/10.33612/diss.159767021

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Propositions

accompanying the dissertation

A computational study on the nature of DNA G-quadruplex structure

by

Kiana Gholamjani Moghaddam

1. The unique characteristics of G-quadruplex scaffolds have made them attractive targets for a range of applications, from cancer therapeutics through to nanodevices (Chapter 1 of this thesis).

2. Molecular dynamics simulations are particularly valuable to the uncovering of the nature of interactions between ligands or proteins and G-quadruplex structures (Chapter 3, 4 and 6 of this thesis).

3. Understanding photoswitchable G-quadruplex structures via computational methods provides an opportunity to develop novel functional nanodevices (Chapter 5 of this thesis).

4. While virtual conferences may lack the benefits of physical events during the COVID-19 pandemic, they provide the opportunity for everyone to attend events from anywhere in the world. I believe that hybrid conferences are a good alternative option in the future, having the best of both worlds.

5. "Learn from yesterday, live for today, hope for tomorrow." (Albert Einstein)

6. "Nothing in life is to be feared. It is only to be understood." (Marie Curie)

7. The number of printed copies of PhD theses should be decreased considering the environmental consequences. We live in a digital world.

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