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University of Groningen Targeting brain death-induced injury van Erp, Anne Cornelie

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University of Groningen

Targeting brain death-induced injury van Erp, Anne Cornelie

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2018

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

van Erp, A. C. (2018). Targeting brain death-induced injury. Rijksuniversiteit Groningen.

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STELLINGEN

Behorende bij het proefschrift

Targeting brain death-induced injury

1. There is a need for evidence-based treatment strategies on how to handle organs from deceased donors – this thesis

2. Metabolic changes during brain death cannot be attributed to mitochondrial dysfunction – this thesis

3. Each organ should receive an organ-specific approach in order to best optimize its quality prior to transplantation – this thesis

4. Optimization of renal quality prior to transplantation should encompass protection against oxidative stress, whereas the liver would benefit from metabolic support – this

thesis

5. Metabolic profiling can be used to show differences between healthy and deceased organs – this thesis

6. Balancing the levels of autophagy and oxidative stress are essential to achieve optimal transplantation outcomes – this thesis

7. Autophagy is impaired in the liver and kidney during brain death – this thesis

8. The Danish hospitality is proof that they have long abandoned their Viking ancestry. 9. Promoveren is net als tophockey, de competitie win je zelden met één briljante actie. 10. In order to grow you have to learn to be comfortable being uncomfortable – Steve

Jennings

11. Als het over een jaar niet meer uitmaakt, hoef je je er nu ook niet druk om te maken –

Berdien van Erp

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