University of Groningen Regenerative Pharmacology for COPD Wu, Xinhui

University of Groningen

Regenerative Pharmacology for COPD Wu, Xinhui

DOI:

10.33612/diss.157528459

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Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Wu, X. (2021). Regenerative Pharmacology for COPD. University of Groningen. https://doi.org/10.33612/diss.157528459

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Propositions related to the present thesis

Stellingen behorende bij het proefschrift

Regenerative Pharmacology for COPD

By Xinhui Wu

1. Targeting the imbalance of the canonical and non-canonical WNT signalling pathway may restore alveolar repair in COPD (this thesis).

2. ROCK inhibition is a promising therapeutic strategy to support lung repair (this thesis).

3. Cigarette smoke not only injures your lung but also your circadian clock, while PGE2 and PGI2 analogues potentially restore them (this thesis).

4. Diesel exhaust particles (DEP) distorted the crosstalk between alveolar epithelial progenitor and its fibroblast niche, which can be prevented by antioxidants NAC and MitoQ (this thesis).

5. The lung organoid, a mini lung, opens a new window into the study of pulmonary diseases and drug discovery (this thesis).

6. Every science begins as philosophy and ends as art; it arises in hypothesis and flows into achievement (Will Durant).

7. Research is what I’m doing when I don’t know what I’m doing.

8. Foods fill your belly, music soothes your soul, and science enlightens your brain. 9. 选择你所坚持的，坚持你所选择的。Choose what you insist, stick to what you

choose.

10. Nothing can be easily obtained. This is the reason for working hard. 11. In me the tiger sniffs the rose (Siegfried Sassoon). 心有猛虎，细嗅蔷薇。 12. Happiness can be found even in the darkest of times, if one only remembers to