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Changes in chromatin organization of human cells in response to genotoxic stress

Abdel-Halim Mahfouz, H.I.

Citation

Abdel-Halim Mahfouz, H. I. (2009, February 24). Changes in chromatin organization of human cells in response to genotoxic stress. Retrieved from https://hdl.handle.net/1887/13517

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/13517

Note: To cite this publication please use the final published version (if applicable).

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Acknowledgements

First of all, I am greatly expressing all praise to ‘Allah’ the most merciful, for giving me patience, self-power and ability to accomplish this work.

I would like to express my sincere thanks and appreciation to all who helped me during the past years in The Netherlands and in Egypt. My gratitude goes to the Mission Department in the Ministry of Higher Education, the Egyptian government for granting me the scholarship at the beginning of my stay in The Netherlands. I would like to extend my sincere gratitude to Prof.

Dr. A.T. Natarajan and Prof. Dr. F.M. Badr for processing the scholarship, inviting and accommodating me in Leiden. The help of Prof. Dr. Bert van Zeeland to arrange the first accommodation in Plantage is much appreciated. I am deeply indebted to Prof. Dr. Leon Mullenders, who offered me the opportunity to complete my PhD education in Leiden University. His understanding and continuous support at work and in person is appreciated.

Thank you Leon, your guidance and valuable and critical feedback have contributed enormously to the experimental work and to the thesis. I thank with gratefulness Dr. Jan Boei for helping me during the course of this study. His experience with the FISH technique and computer work has contributed greatly to the results. We had very useful and critical discussions that improved all parts of the manuscript.

I would like to express my great thanks to Dr. Albert Pastink for critical reading of the manuscript, for his important comments and suggestions and the translation of the summary into Dutch. I would like also to thank Dr. Harry Vrieling for his support. I am grateful to Dr. Barbara Godthelp for being there in the final stage of my work and for valuable discussions and suggestions to improve the manuscript. The effort of Dr. Wouter Ferro in arranging the courses and workshops required for all PhD students is very appreciated. I would like to thank Dr. Firouz Darroudi and Dr. Paul van Buul for helpful discussions and suggestions.

I thank all the staff and colleagues in the Department of Toxicogenetics. The assistance of Xiao, Mattie, Janna and Sylvia at the beginning of my study is much appreciated. Janna thanks for your kind support. The help of Wouter in culturing cells is also appreciated. Special thanks go to Matthieu for helping with computer work during the past years. I am grateful to Marijke, Jane and Ingrid for handling all paper work. Thanks a lot Marijke for everything you did since the start of my scholarship until the defense of my PhD. Leo, you were the first person

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I saw when I arrived at The Netherlands, thanks for being with me and I enjoyed a lot your presence in the lab. I would like also to mention with special thanks neighbors in the Boerhaavelaan and friends in both The Netherlands and Egypt for continuous support and sharing special moments.

I would like to express my gratitude to the staff of the Faculty of Science, Suez Canal University for extending my scholarship until now. Special thanks go to my friends, colleagues and all the staff of the Department of Zoology.

My deepest and sincere thanks are always to my parents, sisters and brother for their constant support and prayers.

Howyda

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