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Macrophage-targeted PET imaging of Rheumatoid Arthritis
Gent, Y.
2015
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citation for published version (APA)
Gent, Y. (2015). Macrophage-targeted PET imaging of Rheumatoid Arthritis: opportunities for early diagnostics
and therapy monitoring.
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CONTENTS
Chapter 1 Introduction 7
PART I Visualization of subclinical synovitis in rheumatoid arthritis
Chapter 2 Present role of positron emission tomography in diagnosis 20 and monitoring of peripheral inflammatory arthritis:
a systematic review.
Arthritis Care Res 2014; 66:120-130
Chapter 3 Macrophage positron emission tomography imaging as a 46 biomarker for preclinical rheumatoid arthritis:
findings of a prospective pilot study.
Arthritis Rheum 2012;64:62-66
Chapter 4 Three-year clinical outcome following baseline magnetic 58 resonance imaging in anti-citrullinated protein antibody-positive
arthralgia patients: an exploratory study.
Arthritis Rheumatol 2014;66:2909-10
Chapter 5 Detection of subclinical synovitis in macrophage targeting and 71 positron emission tomography in patients with rheumatoid arthritis without clinical arthritis.
J Rheumatol 2014; 41:2145-52
Chapter 6 Subclinical synovitis detected by macrophage PET, but not MRI, is 89 related to short-term flare of clinical disease activity in
early RA patients
Submitted for publication
Part II Novel macrophage-targeting PET tracers
Chapter 7 Promising potential of new generation translocator protein tracers 103 providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis
Arthritis Res Ther 2014;16:R70
Chapter 8 Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate 126
for macrophage targeting in a rat model of arthritis
Arthritis Res Ther 2013,15:R37
Chapter 9 Discussion and future perspectives 150
Summary 157
Samenvatting 160
List of publications 164
Dankwoord 165