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University of Groningen Membrane fusion of influenza and chikungunya viruses Blijleven, Jelle

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University of Groningen

Membrane fusion of influenza and chikungunya viruses Blijleven, Jelle

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2018

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Blijleven, J. (2018). Membrane fusion of influenza and chikungunya viruses: Mechanisms inferred from single-particle experiments. Rijksuniversiteit Groningen.

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Propositions

accompanying the thesis

Membrane Fusion of Influenza and Chikungunya

Viruses

by Jelle Blijleven

1. Creating influenza viruses with variable hemagglutinin den-sities will help to refine our understanding of influenza fu-sion.

2. Chikungunya fusion is mediated by multiple E1 trimers. 3. The observed CHK-152 dissociation and resulting fusion

yield imply low-pH inactivation of E1 proteins.

4. The universalities identified in viral fusion tell us we still do not understand the fundamentals.

5. Collaboration is more essential to science than competition. 6. The lifestyle of the rich perpetuates the poverty of the rest. 7. Having children vaccinated is very effective and important, and this needs to be disseminated broadly in light of de-creasing awareness.

8. World population growth needs to be addressed in order to move to a sustainable future.

9. Publishing null results in science should be rewarded. 10. The aviation industry is the largest elephant in the room

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