University of Groningen
Brain and retinal macro- and microvasculature Li, Youhai
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Publication date: 2018
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Li, Y. (2018). Brain and retinal macro- and microvasculature: Response to ischemic and hyperglycemic stress. University of Groningen.
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Brain and retinal macro- and
microvasculature
Response to ischemic and hyperglycemic stress
Cover design & Layout: Youhai Li (Xueying Feng supplies the paintings) Printed by: IPSKAMP Printing
Youhai Li
Brain and retinal macro- and microvasculature Response to ischemic and hyperglycemic stress
ISBN (printed): 978-94-034-0994-8 ISBM (digital): 978-94-034-0993-1
Copyright © Youhai Li, 2018
All rights reserved. No part of this publication maybe reproduced or transmitted in any form or by any means without permission of the author.
Brain and retinal macro- and
microvasculature
Response to ischemic and hyperglycemic stress
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the Rector Magnificus Prof. E. Sterken
and in accordance with
the decision by the College of Deans.
This thesis will be defended in public on Monday 15 October 2018 at 9.00 hours
by
Youhai Li
born on 9 October 1984 in Anhui, China
Supervisors
Prof. Dr. Han Moshage Prof. Dr. Dr. Lothar Schilling
Co-supervisor Dr. Jan Kamps
Assessment committee Prof. Dr. G. (Ingrid) Molema Prof. Dr. Jan-Luuk Hillebrands Prof. Dr. Hans-Peter Hammes
Paranymphs Dr. Jing Wang
Dayang Erna Zulaikha
CONTENTS
Chapter 1
General introduction
Chapter 2
Enhancement of bradykinin-induced relaxation by focal brain ischemia in the rat middle cerebral artery: Receptor expression upregulation and activation of multiple pathways
Chapter 3
A novel method to isolate retinal and brain microvessels from individual rats: Microscopic and molecular biological characterization and application in hyperglycemic animals
Chapter 4
Comparative transcriptome analysis of inner retinal barrier and blood-brain barrier in rats
Chapter 5
Responses of retinal and brain microvasculature to diabetes revealed by global expression profiling Chapter 6 General discussion Appendices Summary Nederlandse samenvatting List of publications Acknowledgments 澳 澳 澳 澳
