University of Groningen
The oligomeric protein interference assay method for validation of antimalarial targets
de Assis Batista, Fernando
DOI:
10.33612/diss.94898872
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Publication date:
2019
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
de Assis Batista, F. (2019). The oligomeric protein interference assay method for validation of antimalarial
targets. University of Groningen. https://doi.org/10.33612/diss.94898872
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L
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UBLISHED
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14. F. A. Batista, S. S. Bosch, S. Butzloff,S. Lunev, K. A. Meissner, M Linzke, A. R. Romero, C. Wang,I. B. Müller, A. S. S. Dömling, M. R. Groves and C. Wrenger. Oligomeric protein
in-terference validates druggability of aspartate interconversion in Plasmodium falciparum.
MicrobiologyOpen e779, (2019).
13. S. Lunev, S. Butzloff, A. R. Romero, M. Linzke, F. A. Batista, K. A. Meissner, I. B. Müller, A. Adawy, C. Wrenger and M. R. Groves. Oligomeric interfaces as a tool in drug discovery: Specific
interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro,PLoS ONE 13, 4, e0195011 (2018).
12. S. Lunev, S. S. Bosch, F. A. Batista, C. Wang, J. Li, M. Linzke, P. Kruithof, G. Chamoun, A. S. S. Dömling, C. Wrenger, and M. R. Groves, M. R. Identification of a non-competitive inhibitor of
Plasmodium falciparum aspartate transcarbamoylase,Biochemical and Biophysical Research Communications 497, 3, 835-842 (2018).
11. M. B. Martins, M. Marcello, F. A. Batista, K. C. Peres, M. Meneghetti, M. A. L. Ward, E. C. S. C. Etchebehere, L. V. M. Assumpcao and L. S. Ward. Serum interleukin measurement may help
identify thyroid cancer patients with active disease,Clinical biochemistry 52, p. 1-7 (2018). 10. P. A. Boonstra, J. A. Gietema, A. J. Suurmeijer, M. R. Groves, F. A. Batista, E. Schuuring and A.
K. L. Reyners, Tyrosine kinase inhibitor sensitive PDGFR. mutations in GIST: Two cases and
review of the literature,Oncotarget 8, 65, p. 109836-109847 (2017).
9. F. A. Batista, M. Marcello, M. B. Martins, K. C. Peres, U. O. Cardoso, A. C. D. N. da Silva, N. E. Bufalo, F. A. Soares, M. J. da Silva, L. V. M Assumpcao and L. S. Ward. Diagnostic utility of
DREAM gene mRNA levels in thyroid tumours.Archives of Endocrinology and Metabolism
62, p. 205-211 (2017).
8. K. A. Meissner, S. Lunev, Y-Z. Wang, M. Linzke, F. A. Batista, C. Wrenger and M. R. Groves.
Drug Target Validation Methods in Malaria - Protein Interference Assay (PIA) as a Tool for Highly Specific Drug Target Validation,Current Drug Targets 18, 9, p. 1069-1085 (2017).
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126 LIST OFPUBLICATIONS
7. S. Lunev, F. A. Batista, S. S. Bosch, C. Wrenger, and M. Groves. Identification and Validation
of Novel Drug Targets for the Treatment of Plasmodium falciparum Malaria: New Insights.,in
Current Topics in Malaria, p. 235-265 (2016).
6. S. Lunev, S. S. Bosch, F. A Batista, C. Wrenger, and M. R. Groves. Crystal structure of truncated
aspartate transcarbamoylase from Plasmodium falciparum.,Acta Crystallographica Section F: Structural Biology Communications, 72(7) p. 523-533 (2015).
5. F. A. Batista, L. S Ward, M. Marcello, M. B. Martins, K. C. Peres, C. Torricelli, N. E. Bufalo, F. A. Soares, M. J. da Silva, and L. V. M. Assumpcao, L. V. M. Gene expression of thyroid-specific
transcription factors may help diagnose thyroid lesions but are not determinants of tumor progression,Journal of endocrinological investigation, 39, 4 p. 423-429 (2016).
4. F. A. Batista. Analysis of expression profile of TTF-1, FOXE1, PAX8 and DREAM genes in
pa-tients with thyroid nodules.Dissertation, School of Medical Sciences, University of Campinas (2015).
3. M. Marcello, L. L. Cunha, F. A. Batista and L. S. Ward. Obesity and Thyroid Cancer.In Obesity:
A Practical Guide p. 221-234 (2015).
2. M. B. Martins, M. Marcello, F. A. Batista, L. L. Cunha, E. C. Morari, F. A. Soares, J. Vassalo and L. S. Ward. CD8+ TIL Recruitment May Revert the Association of MAGE A3 with Aggressive
Features in Thyroid Tumors.Journal of immunology research, 921864 (2014).
1. M. Marcello, L. L. Cunha, F. A. Batista and L. S. Ward. Obesity and Thyroid Cancer. Endocrine-Related cancer 21(5) T255 (2014).
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UBMITTED
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3. F. A. Batista, B. B. Gyau, S. Bosch, S. Lunev, C. Wang, J. F. Vilacha, C. Wrenger, M. R. Groves.
Protein Interference Assay (PIA) offers a Novel Avenue towards the Validation of Antimalarial Target Candidates.
2. S S. Bosch, S. Lunev, F. A. Batista, M. R. Groves, C. Wrenger. Drug target validation of aspartate
transcarbamoylase from Plasmodium falciparum.
1. M. B. Martins, M. Marcello, F. A. Batista, K. C. Peres, M. Meneghetti, E. C. S. C. Etchebehere, L. V. M. Assumpção, L. S. Ward. Polymorphisms In Il-2 And Il-6r Increase Serum Levels of the
LIST OFPUBLICATIONS
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3. F. A. Batista, J. M. Wielenga, S. L. R. Yan, C. Wrenger and M. R. Groves. Identification of novel
inhibithors of dihydroorotate dehydrogenase from Plasmodium falciparum.
2. J. P. Wibowo, F. A. Batista, N. van Oosterwijk, M. R. Groves and W.J. Quax. Crystal structure
and kinetic studies reveal inhibition mechanism of phenylthiourea on PvdP Pseudomonas aeruginosa.
1. F. A. Batista, S. S. Bosch, M.Linzke, S. Lunev, C. Wrenger and M. R. Groves. Ribose-phosphate
