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Gut permeability and myocardial damage in paediatric cardiac surgery Malagon, Ignacio

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Gut permeability and myocardial damage in paediatric cardiac surgery Malagon, Ignacio

Citation

Malagon, I. (2005, December 1). Gut permeability and myocardial damage in paediatric

cardiac surgery. Retrieved from https://hdl.handle.net/1887/3741

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in theInstitutional Repository of the University of Leiden Downloaded from: https://hdl.handle.net/1887/3741

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Gut permeability and myocardial

damage in paediatric cardiac surgery

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ISBN 9090197214

© 2005 I Malagon, Leiden The Netherlands. Except chapters tw o and six (copyright 2005, O xford U niversity Press), chapter three (copyright 2005, Elsevier), and chapter four (copyright 2005, Lippincott W illiam and W ilkins).

Front cover designed by C lara Malagon, back cover designed by Elias Malagon.

Printed by Pasmans offsetdrukkerij bv D en H aag

Financial support for the printing of this thesis w as provided by; Roche D iagnostics, The Netherlands.

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Gut permeability and myocardial damage in

paediatric cardiac surgery

PROEFSCHRIFT

ter verkrijging van de graad van Doctor aan de Universiteit Leiden,

op gezag van de Rector Magnificus Dr. D.D. Breimer,

hoogleraar in de faculteit der Wiskunde en Natuurwetenschappen en die der Geneeskunde,

volgens besluit van het College voor Promoties

te verdedigen op donderdag 1 December 2005 klokke 14:15 uur

door

Ignacio Malagon geboren te Madrid

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Promotiecommissie

Promotoren Prof. Dr. J G Bovill Prof. Dr. M G Hazekamp

Referent Prof. Dr. J L V incent (Brussels) Overige leden Prof. Dr. J W van Kleef

Prof. Dr. P C M van den Berg Dr. W Onkenhout

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CONTENT

Chapter 1 Introduction Section 1

Gut permeability and paediatric cardiac surgery Chapter 2

Gut permeability in paediatric cardiac surgery Chapter 3

Dexamethasone reduces gut permeability in paediatric cardiac surgery Chapter 4

Gut permeability in neonates following a stage I Norwood procedure Chapter 5

Rhamnitol is a metabolite of rhamnose in man Section 2

Cardiac Troponin T and paediatric cardiac surgery Chapter 6

Effect of three different anaesthetic agents on the postoperative production of cardiac troponin T in paediatric cardiac surgery

Chapter 7

Effect of dexamethasone on postoperative cardiac troponin T production in paediatric cardiac surgery

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