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The interplay between cholesterol and inflammation in the evolution of atherosclerosis

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The interplay between cholesterol and inflammation in the evolution of atherosclerosis

Verschuren, L.

Citation

Verschuren, L. (2009, January 22). The interplay between cholesterol and inflammation in the evolution of atherosclerosis. Retrieved from https://hdl.handle.net/1887/13415

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/13415

Note: To cite this publication please use the final published version (if applicable).

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List of publications

203 List of Publications

L. Verschuren, J. de Vries-Van der Weij, S. Zadelaar, R. Kleemann and T. Kooistra. LXR agonist suppresses atherosclerotic lesion growth and promotes lesion regression in

ApoE*3Leiden mice: time course and potential mechanisms. Journal of Lipid Research. in press

L. Verschuren*, R.Kleemann*, M.J. van Erk, Y.i Nikolsky, N.H.P. Cnubben, E.R. Verheij, A.K. Smilde, H.F.J. Hendriks, S.Zadelaar, G.J. Smith, V. Kaznacheev, A. Melnikov, E.

Hurt-Camejo, J. van der Greef, B. van Ommen, and T. Kooistra. Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis. Genome Biology 2007 Sep 24;8(9):R200

S. Zadelaar, R. Kleemann, J. de Vries-Van der Weij, L. M. Havekes, H. M. Princen, L.

Verschuren, T. Kooistra.Mouse models for atherosclerosis and pharmaceutical modifiers.

Review. Arterioscler Thromb Vasc Biol. 2007 Aug 27(8):1706-21.

Rein D, Schijlen E, Kooistra T, Herbers K, Verschuren L, Hall R, Sonnewald U, Bovy A, Kleemann R. Transgenic flavonoid tomato intake reduces C-reactive protein in human C- reactive protein transgenic mice more than wild-type tomato. Journal of Nutrition. 2006 Sep;136(9):2331-7.

Verschuren L*, Kooistra T*, van der Weij J, Koenig W, Toet K, Princen HM, Kleemann R.

Fenofibrate Reduces Atherogenesis in ApoE*3Leiden Mice. Evidence for Multiple Antiatherogenic Effects Besides Lowering Plasma Cholesterol. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2322-30.

Verschuren L, Lindeman JH, van Bockel JH, Abdul-Hussein H, Kooistra T, Kleemann R.

Up-regulation and coexpression of MIF and matrix metalloproteinases in human abdominal aortic aneurysms. Antioxid Redox Signal. 2005 Sep-Oct;7(9-10):1195-202.

Verschuren L, Kleemann R, Offerman EH, Szalai AJ, Emeis SJ, Princen HM, Kooistra T.

Effect of low dose atorvastatin versus diet- induced cholesterol lowering on atherosclerotic

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List of publications

204

lesion progression and inflammation in ApoE*3-Leiden transgenic mice. Arterioscler Thromb Vasc Biol. 2005 Jan; 25(1):161-7.

Kleemann R, Verschuren L, De Rooij BJ, Lindeman J, De Maat MM, Szalai AJ, Princen HM, Kooistra T. Evidence for anti-inflammatory activity of statins and PPAR{alpha}- activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro. Blood 2004 Jun 1; 103(11):4188-94.

Kleemann R, Gervois P, Verschuren L, Princen H.M.G, Kooistra T. Fibrates down- regulate IL-1-stimulated C-reactive protein gene expression in human hepatocytes by reducing nuclear p50-NF-κB~C/EBP-β-complex formation. Blood 2003; 101, 545-551.

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