Cover Page
The handle
http://hdl.handle.net/1887/80838
holds various files of this Leiden University
dissertation.
Author: Hoof, M.J. van
Marie-José van Hoof
Unresolved-disorganized attachment, psychopathology, and the adolescent brain. Funding: grants from WOP GGZ Rivierduinen and Hilly de Roever-Bonnet fonds, Society of Dutch Female Doctors (VNVA) to M.J. van Hoof; Grant from LUMC vrije beleidsruimte to prof. dr. R.R.J.M. Vermeiren; supervision by (em.) prof. dr. M.H. van IJzendoorn, previously Faculty of Social Sciences Leiden University (SPINOZA Award), currently Erasmus University and University of Cambridge; The printing of this thesis was sponsored by M.A.O.C. Gravin van Bylandt Stichting, the Hague.
Cover design: Marie-José van Hoof Gouache: Femme déchirée
Artist: Manolo Ruiz-Pipó (Granada, 1929- Agen, 1998)
reproduction with permission from his heirs Orlando and Flavio Ruiz van Hoof Lay-out: Marie-José van Hoof
Printed by: Gildeprint – Enschede
ISBN 9789463239455
© M.J. van Hoof, Oegstgeest, the Netherlands
Unresolved-Disorganized Attachment,
Psychopathology, and the Adolescent Brain
PROEFSCHRIFT
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties te verdedigen op donderdag 21 november 2019
klokke 12.30 uur
door
Marie-José van Hoof geboren te Bakel en Milheeze
Promotores
Prof. dr. R.R.J.M. Vermeiren
Prof. dr. M.H. van IJzendoorn Erasmus Universiteit Rotterdam;
University of Cambridge
Copromotor
Dr. M.M.E. Hendricx-Riem Universiteit van Tilburg Promotiecommissie
Prof. dr. A.M. van Hemert Prof. dr. B.M. Elzinga
“How wonderful it is that nobody need wait a single moment before starting to improve the world!”
CONTENTS
PROLOGUE 13
GENERAL INTRODUCTION
CHAPTER 1 19
SECTION I: ATTACHMENT AND EMOTION REGULATION
CHAPTER 2 41
Attachment representation in adolescent clinical and non-clinical groups
Marie-José van Hoof, Natasja D.J. van Lang, Sandra Speekenbrink, Marinus H. van IJzendoorn, Robert R.R.J.M. Vermeiren (2015). Adult Attachment Interview differentiates adolescents with Childhood Sexual Abuse from those with clinical depression and non-clinical controls. Attachment & Human Development,
17(4): 354-375. http://dx.doi.org/10.1080/14616734.2015.1050420 . Epub
2015, June 5.
CHAPTER 3 63
Attention bias and emotional face processing in adolescent clinical and non-clinical groups
SECTION II: ATTACHMENT, PSYCHOPATHOLOGY AND NEUROIMAGING
CHAPTER 4 89
Unresolved-disorganized attachment and psychopathology in grey matter and associated resting state functional connectivity of the adolescent brain
Marie-José van Hoof, Madelon Riem, Amy Garrett, Nienke Pannekoek, Nic van der Wee, Marinus van IJzendoorn, Robert Vermeiren (2019). Unresolved-disorganized attachment associated with smaller hippocampus and increased functional connectivity beyond psychopathology. Journal of Traumatic Stress,
32, 742-752. https://doi.org/10.1002/jts.22432 Epub online 2019; July 30.
CHAPTER 5 117
Unresolved-disorganized attachment and General Psychopathology Factor in white matter tracts of the adolescent brain
M.M.E. Riem*, M.J. van Hoof*, A.S. Garrett, S.A.R.B. Rombouts, N.J.A. van der Wee, M.H. van IJzendoorn , R.R.J.M. Vermeiren (2019). General psychopathology factor and unresolved-disorganized attachment uniquely correlated to white matter integrity using diffusion tensor imaging. Behavioral
Brain Research, 359: 1-8. https://doi.org/10.1016/j.bbr.2018.10.014 . Epub
online 2018; Oct 9. *shared first authorship
CHAPTER 6 143
Unresolved-disorganized attachment and psychopathology in resting state functional connectivity of the amygdala
Marie-José van Hoof*, Madelon M.E. Riem*, Amy S. Garrett, Nic van der Wee, Marinus van IJzendoorn, Robert R.J.M. Vermeiren (2019). Unresolved-disorganized attachment adjusted for a General Psychopathology Factor associated with atypical amygdala resting-state functional connectivity.
European Journal of Psychotraumatology, 10(1), 1583525; https://doi.org/10.10
SUMMARY AND GENERAL DISCUSSION
CHAPTER 7 171
REFERENCES 191 APPENDICES 229
- STUDY DESIGN EPISCA - MEASUREMENT
- EMOTIONAL FACES TASK
SUMMARY IN DUTCH | SAMENVATTING 233 ACKNOWLEDGEMENTS 251
CURRICULUM VITAE 253
PORTFOLIO 257 LIST OF CONTRIBUTING AUTHORS 279
