University of Groningen
Through ketamine fields
Viana Chaves, Tharcila
DOI:10.33612/diss.107955714
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Publication date: 2019
Link to publication in University of Groningen/UMCG research database
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Viana Chaves, T. (2019). Through ketamine fields: pain and afterglow. Rijksuniversiteit Groningen. https://doi.org/10.33612/diss.107955714
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Through ketamine fields
pain and afterglow
by
Through ketamine fields: pain and afterglow
ISBN printed book 978-94-034-2237-4 ISBN pdf version 978-94-034-2236-7
Cover design and thesis layout Elisa Calamita, persoonlijkproefschrift.nl Printed by Ipskamp Printing, proefschriften.net Printed on recycled paper
Copyright © 2019 Tharcila Viana Chaves
All rights reserved. No part of this thesis may be reproduced, stored or transmitted in any way or by any means without the prior permission of the author, or when applicable, of the publishers of the scientific articles.
Through ketamine fields
Pain and afterglow
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
woensdag 18december2019 om 12:45 uur
door
Tharcila Viana Chaves
geboren op 13 oktober 1981 te Santo André, Brazilië
Through ketamine fields
Pain and afterglow
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
woensdag 18december2019 om 12:45 uur
door
Tharcila Viana Chaves
geboren op 13 oktober 1981 te Santo André, Brazilië
Paranimfen Lemke Kraan Olaf Gorter Promotor Prof. dr. B. Wilffert Co-promotor Prof. dr. Z.M. Sanchez Beoordelingscommissie
Prof. dr. A.J.M. Loonen Prof. dr E.N. van Roon Prof. dr. B.W.J.H. Penninx
Paranimfen Lemke Kraan Olaf Gorter Promotor Prof. dr. B. Wilffert Co-promotor Prof. dr. Z.M. Sanchez Beoordelingscommissie
Prof. dr. A.J.M. Loonen Prof. dr E.N. van Roon Prof. dr. B.W.J.H. Penninx
Contents
Chapter 1 Introduction 9
From the dance floor to the mainstream scientific research Aims and outline of this thesis
Chapter 2 Oral ketamine for the treatment of pain and
treatment-resistant depression 17
Chapter 3 Special features of special K: applications for pain and
depression treatments 37
Chapter 4 The use of ketamine to cope with depressive symptoms: a
qualitative analysis of the discourses posted on a popular online forum
49
Chapter 5 Ketamine as a new management tool for persistent physical
and mental pain 71
Chapter 6 Overdoses and deaths related to the use of ketamine and its
analogues: a systematic review 81
Chapter 7 General discussion 105
Addendum Appendix 1: Table - Ketamine for depression studies
(supplementary content of chapter 2) 118 Appendix 2: Table – Ketamine for pain studies
(supplementary content of chapter 2) 146 Appendix 3: References list of the tables presented in
appendices 1 and 2 168
Summary 176
Samenvatting (summary in Dutch) 178 Resumen (summary in Spanish) 181 Resumo (summary in Portuguese) 183 Résumé (summary in French) 185 Publication list of Tharcila Chaves 187 About the author 188 Acknowledgements 189
