ARTICLE II

In this present work, we present the application of protein- templated DCC based on this promising scaffold, using endothiapepsin as a target protein.. Afterwards, the hit compound

Throughout this thesis, we focus on applying DCC to various projects. The main achievements are: 1) the description of the in-house protocol of DCC, in which aspects like

In de laatste twee hoofdstukken wordt gebruik gemaakt van endothiapepsin in eiwit-gerichte (eg) DCC. Endothiapepsin behoort tot de familie van de aspartaatproteasen. Deze

In den letzten beiden Kapiteln wurde Endothiapepsin für Protein-vermittelte DCC (ptDCC) verwendet. Endothiapepsin gehört zur Familie der

Dear Rolf, I would like to sincerely thank you for being my co-supervisor from Saarbrücken and for your support in all the events I organised at HIPS.. There are more professors whom

In the last two chapters, endothiapepsin was used for protein-templated DCC (ptDCC). Endothiapepsin belongs to the family of the aspartic proteases, which are involved in for

Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright

However, for the regular use of synthetic macrocycles in drug discovery, three main problems have to be solved, which the research in this thesis is focused