University of Groningen
Radiation-induced cardiac toxicity in breast cancer patients van den Bogaard, Veerle
DOI:
10.33612/diss.144684776
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Publication date: 2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
van den Bogaard, V. (2020). Radiation-induced cardiac toxicity in breast cancer patients. University of Groningen. https://doi.org/10.33612/diss.144684776
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Stellingen behorende bij het proefschrift
Radiation-induced cardiac toxicity in breast cancer patients
1. The normal tissue complication probability model for radiation-induced acute coronary events including the left ventricle V5 performs better than the model including the mean heart dose. (This thesis)
2. The dose to the coronary arteries predicts subclinical systolic dysfunction better than dose to the myocardium. (This thesis)
3. The risk of developing an acute coronary event is almost 5 times higher in breast cancer patients with a high pre-treatment coronary artery calcium score. (This thesis) 4. The challenges of contouring the coronary arteries for large cohorts of breast cancer
patients can be solved using our own developed auto-segmentation tool instead of manual contouring or using an atlas based auto-segmentation method. (This thesis) 5. For patients with an atherosclerotic plaque, the mean dose to these atherosclerotic
plaques is more relevant for the development of acute coronary events than the mean dose to the whole heart, left ventricle or left anterior descending coronary artery. (This thesis)
6. Specializing in the field of oncology is a constant reminder about what is important in life.
7. Cancer care will never be the same again after the COVID-19 pandemic. 8. Constitutive response to when something turns up is YES. (Jim Smith)
9. Nothing great was ever achieved without enthusiasm. (Ralph Waldo Emerson)
10. I didn’t want to just know names of things. I remember really wanting to know how it all worked. (Elizabeth Blackburn)
