University of Groningen
Metabolic capabilities of Lactococcus lactis Hernandez-Valdes, Jhonatan
DOI:
10.33612/diss.130772158
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Publication date: 2020
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Hernandez-Valdes, J. (2020). Metabolic capabilities of Lactococcus lactis: Flavor, amino acids and phenotypic heterogeneity. University of Groningen. https://doi.org/10.33612/diss.130772158
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Stellingen Propositions
Behorende bij het proefschrift Pertaining to the dissertation
Metabolic capabilities of Lactococcus lactis:
Flavor, amino acids and phenotypic heterogeneity Jhonatan A. Hernandez-Valdes
1. Microorganisms lose the production of costly metabolites, but survive by acquiring these metabolites from others or from their environment. This thesis, Chapter 1. 2. Serendipity arises from the ability to see things from different angles.
3. Studying amino acid auxotrophies in bacteria is a challenging work because the prediction of these auxotrophies is only based on whether all the genes of a biosynthetic pathway are present. This thesis, Chapter 9.
4. Due to the genomic revolution, we can isolate a bacterium, for example from our skin, and obtain its genome sequence in few weeks. However, I am more amazed that, even for model organisms, how many genes have not even been given a name due to a lack of knowledge about their function.
5. Thousands of years ago, wild Lactococcus lactis started their journey into domestication. Enhanced fermentative capacities were and remain a goal for Neolithic farmers and dairy researchers.
6. Scientific research driven by curiosity aims to understand how nature works. I believe this curiosity is the foundation of many scientific discoveries.
7. Amino acid auxotrophies illustrate the result of the lactococcal adaptation to the nitrogen-rich milk environments and reflect how well suited these bacteria currently are to the environment in which they live. This thesis, Chapter 9.
8. Bacteria are social organisms that live in communities and engage in different interactions such as physical and chemical interactions. For instance, simulating their natural habit allows the production of some secondary metabolites. This thesis, Chapter 8.
9. Many discoveries are derived from visual observation. Therefore, in addition to being beautiful, images can be inspiring and help develop hypotheses.
10. Scientists are artists as well, we are excited about the unknown and we like pushing boundaries.
