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VU Research Portal

Biomarkers and Thiopurines in IBD

Meijer, B.

2017

document version

Publisher's PDF, also known as Version of record

Link to publication in VU Research Portal

citation for published version (APA)

Meijer, B. (2017). Biomarkers and Thiopurines in IBD: when two worlds collide.

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Anna Ashcroft, BSc

Christchurch Hospital, University of Otago, Christchurch, New Zealand

Hans Blokzijl, MD, PhD

University Medical Center Groningen, Rijks University Groningen, Groningen, The Netherlands

Professor Gerd Bouma, MD, PhD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Laura Burgess, BSc

Christchurch Hospital, University of Otago, Christchurch, New Zealand

Minneke J Coenraad, MD, PhD

Leiden University Medical Center, Leiden University, Leiden, The Netherlands

Professor Andrew S Day, MBChB, PhD, FRACP, AGAF

Christchurch Hospital, University of Otago, Christchurch, New Zealand

Nanne K H de Boer, MD, PhD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Professor Robert A de Man, MD, PhD

Erasmus University Medical Center, Erasmus University, Rotterdam, The Netherlands

Luc J J Derijks, PharmD, PhD

Máxima Medical Center, Veldhoven, The Netherlands

Professor Gerard Dijkstra, MD, PhD

University Medical Center Groningen, Rijks University Groningen, Groningen, The Netherlands

James D Falvey, MBChB, PhD

Christchurch Hospital, University of Otago, Christchurch, New Zealand

Professor Christopher M A Frampton, BSc, PhD

Christchurch Hospital, University of Otago, Christchurch, New Zealand

(3)

Professor Richard B Gearry, MBChB, FRACP, PhD

Christchurch Hospital, University of Otago, Christchurch, New Zealand

Frank Hoentjen, MD, PhD

Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands

Teagan Hoskin, BSc

Christchurch Hospital, University of Otago, Christchurch, New Zealand

Jacqui I Keenan, MApplSci, PhD

Christchurch Hospital, University of Otago, Christchurch, New Zealand

Jan-Kees Kneppelhout, MD

St. Anna Hospital, Geldrop, The Netherlands

Joany E Kreijne, MD

Erasmus University Medical Center, Erasmus University, Rotterdam, The Netherlands

Niek N W Leijte, MD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Ronald K Linskens, MD, PhD

St. Anna Hospital, Geldrop, The Netherlands

Professor Chris J J Mulder, MD, PhD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Bas Oldenburg, MD, PhD

University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands

Professor Godefridus J Peters, MD, PhD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Cyriel Y Ponsioen, MD, PhD

Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Dewkoemar Ramsoekh, MD, PhD

VU University Medical Center, VU University, Amsterdam, The Netherlands

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Melek Simsek, MD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Professor Catherine Stedman, MBChB, FRACP, PhD

Christchurch Hospital, University of Otago, Christchurch, New Zealand

Adriaan A van Bodegraven, MD, PhD

VU University Medical Center, VU University, Amsterdam, The Netherlands Zuyderland Medical Center, Sittard-Geleen, The Netherlands

Andrea E van der Meulen, MD, PhD

Leiden University Medical Center, Leiden University, Leiden, The Netherlands

Professor C Janneke van der Woude, MD, PhD

Erasmus University Medical Center, Erasmus University, Rotterdam, The Netherlands

Remco van Egmond, MD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Charlotte K van Everdingen, MD

VU University Medical Center, VU University, Amsterdam, The Netherlands Christchurch Hospital, University of Otago, Christchurch, New Zealand

Sofia A W van Moorsel, PharmD

Zuyderland Medical Center, Sittard-Geleen, The Netherlands

Carin M J van Nieuwkerk, MD, PhD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Abraham J Wilhelm, PharmD, PhD

VU University Medical Center, VU University, Amsterdam, The Netherlands

Dion Wintjens, MD

Maastricht University Medical Center, Maastricht University, Maastricht, The Netherlands

Dennis R Wong, PharmD, PhD

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Meijer B, Gearry RB, Day AS.

The role of S100A12 as a systemic marker of inflammation.

International Journal of Inflammation, 2012. Meijer B, Gearry RB, Day AS.

S100A12 in EDTA plasma - a cautionary tale.

Journal of Crohn’s and Colitis, 2012.

Meijer B, Hoskin T, Ashcroft A, Burgess L, Keenan JI, Falvey JD, Gearry RB, Day AS.

Total soluble and endogenous secretory receptor for advanced glycation endproducts (RAGE) in IBD.

Journal of Crohn’s and Colitis, 2013.

Falvey JD, Hoskin T, Meijer B, Ashcroft A, Walmsley R, Day AS, Gearry RB.

Disease activity assessment in IBD: clinical indices and biomarkers fail to predict endoscopic remission.

Inflammatory Bowel Diseases, 2015. Meijer B, Bouma G, de Boer NKH.

Optimize thiopurine therapy in autoimmune hepatitis.

Clinical Gastroenterology and Hepatology, 2016.

Meijer B, Seinen ML, Leijte N, Mulder CJJ, van Bodegraven AA, de Boer NKH.

Clinical Value of Mercaptopurine after Failing Azathioprine Therapy in Patients with Inflammatory Bowel Disease.

Therapeutic Drug Monitoring, 2016. Meijer B, Mulder CJJ, de Boer NKH.

NUDT15: a novel player in thiopurine metabolism.

Journal of Gastrointestinal and Liver Diseases, 2016.

Dujardin RWG, Meijer B, de Boer NKH, D’Haens GRAM, Löwenberg M.

Usefulness of MCV as surrogate marker for monitoring thiopurine treatment in IBD.

European Journal of Gastroenterology & Hepatology, 2016.

(6)

Meijer B, Mulder CJJ, Peters GJ, van Bodegraven AA, de Boer NKH.

The efficacy of Thioguanine Treatment in IBD: a Systematic Review.

World Journal of Gastroenterology, 2016.

Meijer B*, Simsek M*, Blokzijl H, de Man RA, Coenraad MJ, Dijkstra G, van Nieuwkerk CMJ, Mulder CJJ, de Boer NKH.

Nodular Regenerative Hyperplasia Rarely Leads To Liver Transplantation: a 20-year retrospective study in all Dutch liver transplant units.

United European Gastroenterology Journal, 2016.

Meijer B, Kreijne JE, van Moorsel SAW, Derijks LJJ, Bouma G, Mulder CJJ, Wong DR, van der Woude CJ, van Bodegraven AA, de Boer NKH.

6-methylmercaptopurine induced leukocytopenia during thiopurine therapy in IBD patients.

Journal of Gastroenterology and Hepatology, 2016. Meijer B, Mulder CJJ, van Bodegraven AA, de Boer NKH.

How I treat my IBD patients with thiopurines.

World Journal of Gastrointestinal Pharmacology and Therapeutics, 2016.

Meijer B, Seinen ML, van Egmond R, Bouma G, Mulder CJJ, van Bodegraven AA, de Boer NKH.

Optimizing thiopurine therapy in inflammatory bowel disease amongst two real-life intercept cohorts: effect of allopurinol co-medication?

Inflammatory Bowel Diseases, 2017.

Meijer B, Wilhelm AJ, Bouma G, Mulder CJJ, van Bodegraven AA, de Boer NKH.

Pharmacology of thiopurine therapy in inflammatory bowel disease and complete blood count outcomes: a 5-year database study.

Therapeutic Drug Monitoring, 2017. Meijer B, de Boer NKH.

Do not forget to culture.

Digestive and Liver Diseases, 2017. Meijer B, de Boer NKH.

All thiopurines are equal but some thiopurines are more equal than others.

JAMA Oncology, 2017. Meijer B, de Boer NKH.

Accelerating with the brakes on?

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Meijer B*, van Everdingen CK*, Ramsoekh DR, Stedman C, Frampton CM, Mulder CJJ, Bouma G, de Boer NKH, Gearry RB.

Transient elastography to detect liver fibrosis in patients with inflammatory bowel disease.

Submitted

Meijer B, Mulder CJJ, Ponsioen CY, van der Woude CJ, van der Meulen AE, Wintjens D, Dijkstra G, Hoentjen F, Oldenburg B, van Bodegraven AA, de Boer NKH, on behalf of the Dutch Initiative on Crohn and Colitis and Parelsnoer Institute.

Methotrexate and thioguanine rescue therapy for conventional thiopurine failing ulcerative colitis patients: a multi-center database study on tolerability and effectiveness.

Submitted

Meijer B, Seinen ML, Hosman T, Linskens RK, Kneppelhout JC, Peters GJ, Mulder CJJ, van Bodegraven AA, de Boer NKH.

Inter-individual variability of xanthine oxidase activity in IBD patients.

Submitted

Simsek M, Meijer B, Mulder CJJ, van Bodegraven AA, de Boer NKH.

Analytical pitfalls of therapeutic drug monitoring of thiopurines in inflammatory bowel disease patients.

Therapeutic Drug Monitoring, 2017.

Simsek M, Meijer B, van Bodegraven AA, de Boer NKH, Mulder CJJ.

Finding hidden treasures in old drugs: The importance of licensing generic drugs and its challenges

Drug Discovery Today, 2017.

de Boer NKH, Peyrin-Biroulet L, Jharap B, Sanderson JD, Meijer B, Atreya I, Barclay ML, Colombel J-F, Lopez A, Beaugerie L, Marinaki AM, van Bodegraven AA, Neurath MF.

Thiopurines in Inflammatory Bowel Disease: a state-of-the-art review.

Submitted

Simsek M*, Meijer B*, Ramsoekh D, Bouma G, van der Wouden EJ, den Hartog B, de Vries AC, Hoentjen F, Dijkstra G, de Boer SY, Jansen JM, van der Meulen AE, Beukers R, Brink MA, Steinhauser T, Oldenburg B, Gilissen LP, Naber TH, Verhagen MA, de Boer NKH, Mulder CJJ.

Natural course of nodular regenerative hyperplasia in thiopurine treated inflammatory bowel disease patients.

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