University of Groningen
The molecular role of Serf2 in development and misfolded protein aggregation
Stroo, Esther
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Publication date: 2018
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Stroo, E. (2018). The molecular role of Serf2 in development and misfolded protein aggregation. Rijksuniversiteit Groningen.
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Stellingen
Behorende bij het proefschrift
"The molecular role of Serf2 in development and misfolded protein
aggregation"
te verdedigen door Esther Stroo
op maandag 7 mei 2018 om 16:15 uur
1. As the human population becomes older, it is essential to understand the processes underlying age-related diseases
2. Loss of Serf2 during development delays growth, which results in incomplete lung development at birth and death because of respiratory failure (This thesis) 3. Serf2 catalyzes amyloid formation of mutant huntingtin and alpha-synuclein
(This thesis)
4. Serf2 is not essential for brain survival (This thesis)
5. Absence of Serf2 during amyloid-beta plaque formation affects the plaque morphotype (This thesis)
6. The limited overlap between mouse models and human diseases, emphasizes the need for experimental replication in multiple models before predicting human outcome
7. No one wants to get old, but no one wants to die young either (Keith Richards) 8. Je bent een expert als je alle fouten gemaakt hebt, die gemaakt kunnen worden
in heel klein gebied (Niels Bohr)
9. If a cluttered desk is a sign of a cluttered mind, of what then is an empty desk a sign? (Albert Einstein)
