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The handle http://hdl.handle.net/1887/32965 holds various files of this Leiden University dissertation

Author: Hezewijk, Marjan van

Title: Tailoring follow-up in early-stage breast cancer

Issue Date: 2015-05-13

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TAILORING FOLLOW-UP IN EARLY-STAGE BREAST CANCER

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Zink Typografie Sheet 2 of 164 - Page ii of 158 Tailoring follow-up in early-stage breast cancer

© M. van Hezewijk, Leiden 2015

ISBN: 978-94-6259-613-9

Lay-out: Zink Typografie (www.zinktypografie.nl) Cover design: Esther Ris (www.proefschriftomslag.nl) Printed by: Ipskamp Drukkers

The research in this thesis was financially supported the Dutch Cancer Society (project number UL 2008-4192) and Pfizer B.V.

Financial support for the printing of this thesis was provided by the Bontius Stichting Doelfonds Klinische Oncologie, Pfizer B.V., Chipsoft B.V., Toshiba Medical Systems Nederland, and Elekta B.V.

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Tailoring follow-up in early-stage breast cancer

PROEFSCHRIFT

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van de Rector Magnificus prof.mr. C.J.J.M. Stolker,

volgens besluit van het College voor Promoties te verdedigen op woensdag 13 mei 2015

klokke 16.15 uur

door Marjan van Hezewijk geboren te ’s-Hertogenbosch

in 1979

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Zink Typografie Sheet 4 of 164 - Page iv of 158 Promotores: Prof.dr. C.A.M. Marijnen

Prof.dr. C.J.H. van de Velde

Co-promotor: Dr. A.N. Scholten, NKI-AvL, Amsterdam

Overige leden: Prof.dr. P.M.P. Poortmans, Radboud UMC, Nijmegen Prof.dr. E.J.T. Rutgers, NKI-AvL/UvA, Amsterdam Prof.dr. A.M. Stiggelbout

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contents

1 Introduction 1

2 Effect of local therapy on locoregional recurrence in postmenopausal women with breast cancer in the Tamoxifen Exemestane Adjuvant

Multinational (TEAM) trial 23

3 Patients’ needs and preferences in routine follow-up for early breast cancer;

an evaluation of the changing role of the nurse practitioner 43

4 Professionals’ opinion on follow-up in breast cancer patients; perceived

purpose and influence of patients’ risk factors 63

5 Costs of different follow-up strategies in early breast cancer: a review of the

literature 81

6 Feasibility of tailored follow-up for patients with early breast cancer 101

7 General discussion 121

Summary 137

Nederlandse samenvatting 145

Publications 153

Curriculum Vitae 155

Woord van dank 157

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Zink Typografie Sheet 6 of 164 - Page vi of 158

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