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University of Groningen Diagnostic and therapeutic challenges in inflammatory eye diseases Wieringa, Wietse Grieco

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University of Groningen

Diagnostic and therapeutic challenges in inflammatory eye diseases

Wieringa, Wietse Grieco

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from

it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date:

2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Wieringa, W. G. (2019). Diagnostic and therapeutic challenges in inflammatory eye diseases.

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Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

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Diagnostic and therapeutic challenges in

inflammatory eye diseases

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Colophon

Copyright © 2019 W.G. Wieringa

All rights reserved. No parts of this publication may be reproduced, stored

in a retrieval system, or transmitted in any form or by any means without

permission of the author and the publisher holding the copyright of the

published articles

Graphic design:

www.studioanne-marijn.com

Printed by:

Gildeprint, Enschede

ISBN printed version: 9789463236218

ISBN digital version: 9789463236225

Printing of this thesis was financially supported by the University Medical Center

Groningen, Prof. Mulder Stichting and Medical Workshop Groningen

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Diagnostic and therapeutic challenges

in inflammatory eye diseases

Proefschrift

ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op maandag 13 mei 2019 om 14.30 uur

door

Wietse Grieco Wieringa

geboren op 26 april 1972 te Leens

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Promotor

Prof. dr. J.M.M. Hooymans

Copromotor

Dr. L.I. Los

Beoordelingscommissie

Prof. dr. H. Bootsma Prof. dr. A. Rothova Prof. dr. N.M. Wulffraat

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TABLE OF CONTENTS

GENERAL

INTRODUCTION - P.6

VISUAL OUTCOME, TREATMENT RESULTS AND PROGNOSTIC FACTORS IN PATIENTS WITH SCLERITIS - P.22 CLINICAL MANIFESTATIONS AND OUTCOME OF SYPHILITIC UVEITIS - P.40 RETINAL DYSTROPHY IN 6 YOUNG PATIENTS WHO PRESENTED WITH INTERMEDIATE UVEITIS - P.58 EFFICACY OF HIGH DOSE METHOTREXATE IN PEDIATRIC NON-INFECTIOUS UVEITIS - P.68

1

2

3

4

5

6

7

8

9

PHYSICAL AND PSYCHOSOCIAL HEALTH IN PEDIATRIC UVEITIS PATIENTS - P.84

RISK FACTORS FOR GLAUCOMA SURGERY IN CHILDHOOD UVEITIS - P.104 FUTURE PERSPECTIVES - P.120 APPENDICES SUMMARY - P.138 NEDERLANDSE SAMENVATTING - P.142 CURRICULUM VITAE - P.148 DANKWOORD - P.150 LIST OF ABBREVIATIONS - P.156

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