University of Groningen
Genotyping and phenotyping epilepsies of childhood Vlaskamp, Danique
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Publication date: 2018
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Vlaskamp, D. (2018). Genotyping and phenotyping epilepsies of childhood. Rijksuniversiteit Groningen.
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PROPOSITIONS
belonging to the thesis
Genotyping and phenotyping epilepsies of childhood
I. Adequate interpretation of genetic data in epilepsy patients depends on deep and careful phenotyping. – this thesis
II. Genetic testing and counseling not only have diagnostic implications, but can also be associated with an increase in psychological well-being.
– this thesis
III. Reverse phenotype studies are instrumental in recognizing a genetic epilepsy phenotype, including its key features and full clinical spectrum.
– this thesis
IV. Identifi cation of genotype-phenotype correlations can help to understand the disease mechanism and to develop precision medicine approaches. – this thesis
V. Evaluation of psychiatric problems in girls and women with
PCDH19 Girls Clustering Epilepsy is strongly recommended. – this thesis
VI. The penetrance of an epilepsy gene may be overestimated due to the selection of patients based on a clinical feature already known to be associated with this gene. – this thesis
VII. A little knowledge is dangerous. So is a lot. – Albert Einstein
VIII. When religion was strong and science weak, men mistook magic for medicine; now when science is strong and religion weak, men mistake medicine for magic. – Thomas Szasz
