University of Groningen
Low-normal thyroid function and cardio-metabolic risk markers
Wind, Lynnda
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Publication date: 2018
Link to publication in University of Groningen/UMCG research database
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Wind, L. (2018). Low-normal thyroid function and cardio-metabolic risk markers. Rijksuniversiteit Groningen.
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1
STELLINGEN
Behorend bij het proefschrift
Low-normal thyroid function and
cardio-metabolic risk markers
1. Low-normal thyroid function may contribute to the pathogenesis of
atherosclerotic cardiovascular disease. – This thesis
2. Variation in thyroid function influences the metabolism of
triglyceride-rich-apoB-containing lipoproteins by effecting apoE regulation. – This thesis
3. The inverse relationship of PON-1 activity with free T4 is not modified
by the presence of the metabolic syndrome. – This thesis
4. Effects of thyroid function status on pro-inflammatory pathways, which relate to enhanced susceptibility to atherosclerotic CVD, are likely to
extend in the euthyroid range. – This thesis
5. The relationship of low-normal thyroid function with pro-atherogenic biomarkers have been demonstrated to be particularly evident in
subjects with diabetes or the metabolic syndrome. – This thesis
6. Altered deoidination of T4 to T3 in adipose tissue may contribute to
enhanced hepatic fat accumulation. – This thesis
7. From a clinical perspective it is relevant to identify those categories of persons that might benefit from thyroid hormone supplementation in
the context of low-normal thyroid function. – This thesis
8. Prediction is very difficult, especially if it’s about the future. – Nils Bohr
9. It is our choices that show what we truly are, far more
than our abilities. – Albus Dumbledore
10. It always seems impossible until it’s done. – Nelson Mandela
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