University of Groningen
Shades of a blue heart
Moreira da Rocha de Miranda Az, Ricardo
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Publication date: 2018
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Moreira da Rocha de Miranda Az, R. (2018). Shades of a blue heart: An epidemiological investigation of depressive symptom dimensions and the association with cardiovascular disease. University of Groningen.
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Shades Of A Blue Heart:
An Epidemiological Investigation Of Depressive
Symptom Dimensions And The Association With
Cardiovascular Disease
Shades Of A Blue Heart
An Epidemiological Investigation Of Depressive Symptom
Dimensions And The Association With Cardiovascular
Disease
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the
Rector Magnificus Prof. Dr. E. Sterken and in accordance with
the decision by the College of Deans. This thesis will be defended in public on
Wednesday 4 July 2018 at 11.00 hours by
Ricardo Moreira da Rocha de Miranda Azevedo
born on 30 August 1987 in Rio de Janeiro, Brazil
Shades of a Blue Heart: An Epidemiological Investigation of Depressive Symptom Dimensions and the Association with Cardiovascular Disease Cover design by Rodrigo Pinheiro & Ricardo de Miranda Azevedo Lay-out by Rodrigo Pinheiro Printed by Printsupport4U BV, www.printsupport4u.nl ISBN: 978-94-034-0750-0 (Printed version) © Copyright Ricardo de Miranda Azevedo, 2018
Shades Of A Blue Heart
An Epidemiological Investigation Of Depressive Symptom
Dimensions And The Association With Cardiovascular
Disease
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the
Rector Magnificus Prof. Dr. E. Sterken and in accordance with
the decision by the College of Deans. This thesis will be defended in public on
Wednesday 4 July 2018 at 11.00 hours by
Ricardo Moreira da Rocha de Miranda Azevedo
born on 30 August 1987 in Rio de Janeiro, Brazil
Shades of a Blue Heart: An Epidemiological Investigation of Depressive Symptom Dimensions and the Association with Cardiovascular Disease Cover design by Rodrigo Pinheiro & Ricardo de Miranda Azevedo Lay-out by Rodrigo Pinheiro Printed by Printsupport4U BV, www.printsupport4u.nl ISBN: 978-94-034-0750-0 (Printed version) © Copyright Ricardo de Miranda Azevedo, 2018
Table of contents
Chapter 1 General introduction 9 Chapter 2 Cognitive/affective and somatic/affective
symptoms of depression in patients with heart disease and the association with cardiovascular prognosis
36
Chapter 3 A bifactor model of the Beck Depression Inventory and its association with medical prognosis after myocardial infarction
74
Chapter 4 Individual Depressive Symptoms and All-cause Mortality in 6,673 Patients with Myocardial Infarction: Heterogeneity Across Age and Sex Subgroups
106
Chapter 5 Investigating The Longitudinal Association of Arterial Stiffness and Carotid Intima-Media Thickness With Depressive Symptom Dimensions in Middle-Aged Individuals
132
Chapter 6 Association of recognized and unrecognized myocardial infarction with depression and anxiety in 125,750 individuals: the LifeLines Cohort Study 158 Chapter 7 General discussion 182 Nederlandse sammenvating 204 Acknowledgements 209 Curriculum vitae 210 Previous SHARE dissertations 211 Supervisor Prof. P. de Jonge Co-supervisor Dr. A.M. Roest Assessment Committee
Prof. A.V. Ranchor Prof. F. Pouwer
Table of contents
Chapter 1 General introduction 9 Chapter 2 Cognitive/affective and somatic/affective
symptoms of depression in patients with heart disease and the association with cardiovascular prognosis
36
Chapter 3 A bifactor model of the Beck Depression Inventory and its association with medical prognosis after myocardial infarction
74
Chapter 4 Individual Depressive Symptoms and All-cause Mortality in 6,673 Patients with Myocardial Infarction: Heterogeneity Across Age and Sex Subgroups
106
Chapter 5 Investigating The Longitudinal Association of Arterial Stiffness and Carotid Intima-Media Thickness With Depressive Symptom Dimensions in Middle-Aged Individuals
132
Chapter 6 Association of recognized and unrecognized myocardial infarction with depression and anxiety in 125,750 individuals: the LifeLines Cohort Study 158 Chapter 7 General discussion 182 Nederlandse sammenvating 204 Acknowledgements 209 Curriculum vitae 210 Previous SHARE dissertations 211 Supervisor Prof. P. de Jonge Co-supervisor Dr. A.M. Roest Assessment Committee
Prof. A.V. Ranchor Prof. F. Pouwer