University of Groningen
Characterization and computation-supported engineering of an ω-transaminase Meng, Qinglong
DOI:
10.33612/diss.172243517
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Publication date: 2021
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Citation for published version (APA):
Meng, Q. (2021). Characterization and computation-supported engineering of an ω-transaminase. University of Groningen. https://doi.org/10.33612/diss.172243517
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ACKNOWLEDGMENTS
I would like to thank all the people who gave me help with my research and the life in the Netherlands during my Ph.D.
Dear Dick, thank you very much for accepting me into your research group and I really appreciate your beneficial supervision. Thank you for all your precious suggestions in every meeting and thanks a lot for your patience to revise my manuscript. In addition, thank you for your critical suggestions to my presentations. I learned a lot from you and it will be very helpful to my future career.
Dear Marco, thank you for your useful and sincerely advice during our group meeting. It is really nice to have a dinner every Sinterklaas at your place.
Dear Hein, thank you for your supervision to my research project and especially in the computational part. Thank you for taking the time to revise my manuscript. I am really happy to see you have more family members now. All my best to you and Xiaoyu.
Dear Andy and Henriette, thank you for your contributions of crystallization in my
research project and also the significant comments in my manuscript. Dear Siewert, I would like to thank you for your swift comments and corrections in our collaborated manuscript.
Dear the committee members, Prof. G.J. Poelarends, Prof. G. Maglia, and Prof. J. Pleiss. I am very grateful to you for spending your time reading and giving valuable comments on my thesis.
Christiaan, you are a responsible and considerable technician. Thank you for all your great
support to our lab work. I wish you all the best in your new career. Sandra, thanks a lot for your kind help regarding the administrative issues in Groningen and making me much easier to focus on the scientific work.
Carlos, we have a great collaboration in transaminase project. You did a really good job
and I learned a lot of the details of computational design from you. Thank you! Nikolas, we also have a great collaboration and thank you for your great job in the crystallization. I like your humor and it is impressive for me that you are pretty cool when you play the instruments.
I have a plenty of memorable and fun time with my officemates (104). Elisa, thanks a lot for your kindness and patience to supervise my first project of Ph.D. and also your generousness to share your research experience to me. I wish you and your families all the best in Cork. Hemant, thank you for your friendship and help when I have general questions in my research especially during the early period of my Ph.D. study. I really miss the delicious food you cooked for us. I wish you a happy life in Germany. Mohammed, my friend Habib, thank you for choosing me as your paranymph in your Ph.D. defense. It is really nice to talk with you about the Egyptian culture and soccer. I wish you all the best in your future career. Milos, it is really great that a good friend sat on my left in the office during almost all of my Ph.D. study. I really appreciate your answers to my silly chemistry questions and thank you for sharing your experience about taking care of the baby. I am very glad to meet your wife Jasna and your little cute Sofia. I wish you and your
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families all the best in Groningen. Yiming, 和你在办公室聊天很开心，也很喜欢和你一起聊 足球。我祝愿你博士生涯一切顺利，早日毕业！
Cate, we almost simultaneously started our Ph.D. study and I really admire your efficient
work style. You are also a helpful person in the lab and I still remember you provided me a very detailed FRESCO protocol when I just joined the lab. I wish you all the best in GECCO. Elvira
(Bombino), although most of the time you do computational work in the office, we still had a nice
conversation in the coffee corner and the blue building during lunchtime. I wish you a good luck in your thesis writing. Nikola, thank you for organizing a lot of activities out of the lab, though I missed many times during weekends, it was still very enjoyable for me to join during weekdays after the lab work. Misun, thank you for sharing your experience about the Ph.D. study during our conversation and it is really cool when you play drum. Martin, we had a good time at the party and all my best to you and Misun in your future life. Gautier, you have a barrel of laughs to make the lab relax, and meanwhile you can also turn to be serious immediately in the lab work. It is really wonderful we watched the semi-final match (world cup 2018) between France and Belgium in the bar. I wish you all the best in Canada. Jeroen, thank you for introducing the Dutch culture during our conversation and I enjoyed that a lot. Simone, that is nice for me you are my second bench-neighbor (after Romero) in the lab and I wish you all the best in GECCO. Yapei, 很高兴看 到你在我攻读博士学位期间加入了这个组，让我在组里可以说更多亲切的母语。祝愿你 早日顺利毕业！Guang, 虽然你加入这个组的时间略短，但我们通过经常一起去餐厅吃午 饭加深了彼此的了解。祝愿你的博士生涯一切顺利！I would also thank other group
members: Hugo, Lur, Andrea, Daniël, and Nyoman, it is a pleasure for me to work in the same group with you.
I would like to thank people from upstairs. Zhi, 很高兴在我博士生涯的大部分时间能 与你这样的朋友相处，你是我科研方面学习的榜样。我祝愿你将来在江南大学工作一切 顺利，一家四口永远幸福安康！Linda, I really enjoy our conversation because you are a humorous girl with a big smile. I wish you all the best to you and your families. Reuben, we have great memories at the conference Chains and I really like your London accent. All my best to you and Ginny. Rudy, we also have a good time at the conference Chains and I really admire your efficient research outputs. Titia, thank you for joining the group discussion and giving nice presentations. Clemens, thank you for your sharp questions in every group meeting.
I am grateful to the former group members. Elvira (Romero), my bench neighbor, you showed a really good example to me in the lab because of your hard working and achievements in science. I really appreciate your help when I had questions in the lab. Sam, thank you for sharing the Indian culture to me and I was also glad to introduce Chinese culture to you. I am really lucky that you have rich experience in terms of transaminases and it made my project go smoothly. Max, you are really talented, not only in science but also in other things. Thank you for all your help when I had stupid questions for you. I wish you can reach a higher level of your scientific work in
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Cambridge and also all my best to you and Cora. Friso, it was great to work with you in the same lab (109), your patient personality and careful attitude to science highly impressed me. I wish you all the best in Roelfes’s group. Haiyan, 周老师，每次和您的交谈让我受益良多，祝您在长沙 的生活和工作一切顺利，希望以后在国内可以再次相聚。I would also like to thank other former group members and former members from upstairs who gave me help and had a good time together: Antonija, Eduardo, Dana, Fabiola, Brenda, Thai, Marzena, Nina, Cyntia, Yans,
Ivana, Sara, Manu, Mathias, Eleonora, Ulises, Anja, JJ.
Dong, Mattijs, Rouèl, Daria, and Luc, thank you all for your great jobs in our projects. I
am glad to be your daily supervisor and it is beneficial for me to improve my teaching skill. I wish you all the best in your next step career.
In addition, I would like to thank my other friends in Groningen and Amsterdam: Gang
Xiang, Yuzhen, Haoqi, Yichen, Yukun, Yang Liu, Min Wu, Xuewen, Stefania, Matteo, Ting Liu, Gongjin, Yanhua, Thierry, Emma, Xiaolong, Juan Wen, etc.
Dear my paranymphs, Ale and Estela. Thank you very much for your great preparation to my Ph.D. defense. Ale, I am grateful for our friendship and I really enjoyed your introduction of Latin culture and Spanish in the office. It is a pity we did not continue our tennis, but I think we still enjoyed that well and it was also great to play squash with you. I wish you and Mel all the best in your future life. Estela, our situation is similar because we are both scholarship Ph.D. students in the same sub-group. We have a nice collaboration in the project of cinnamylamine production and I am really glad to our conversation and scientific discussion. I wish you a good luck for your thesis writing. My wife Yanfei, 老婆，感谢博士这几年以来你对我的鼓励和支持，也要感谢你对 于只能周末相聚的理解。更要谢谢你在经历将近30个小时的漫长生产中为我们这个小家 诞生了一个可爱的小宝贝儿，辛苦了老婆！同时我还要感谢我的父母还有我的岳母不辞 辛苦来到遥远的荷兰帮我们照看孩子，是你们的帮助让我们能顺利完成博士阶段的工 作。
Finally, thank the China Scholarship Council for providing me a fellowship for my Ph.D. study.
