Cover Page
The handle http://hdl.handle.net/1887/39155 holds various files of this Leiden University dissertation
Author: Yiu, Kai-Hang
Title: Advanced clinical applications of cardiac computed tomography and novel echocardiographic modalities
Issue Date: 2016-04-28
Advanced clinical applications of cardiac computed tomography and novel echocardiographic modalities
Kai-Hang Yiu
Advanced clinical applications of cardiac computed tomography and novel echocardiographic modalities
The studies described in this thesis were performed at the Department of Cardiology of Leiden University Medical Center (LUMC), Leiden, The Netherlands
Cover: Kai-Hang Yiu
Layout and Printing: Optima Grafische Communicatie, Rotterdam, the Netherlands
ISBN: 978-94-6169-864-3 Copyright© 2016 Kai-Hang Yiu, Leiden, The Netherlands. All rights reserved. No part of this book may be reproduced or transmitted, in any form or by any means, without permission of the author.
Advanced clinical applications of cardiac computed tomography and novel echocardiographic modalities
Proefschrift
Ter verkrijging van de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker, volgens besluit van het College voor
Promoties te verdedigen
op dinsdag 28 april 2016 klokke 16.15 uur
door Kai-Hang Yiu
Geboren te Hong Kong, in 1977
Promotor Prof. Dr. JJ Bax
Co-promotor Dr. N Ajmone Marsan
Leden promotiecommissie:
Prof. Dr. MJ Schalij Prof. Dr. RJ Klautz Prof. Dr. JW Jukema Prof. Dr. DE Atsma Prof. Dr. TWJ Huizinga Dr. V Delgado
Prof. Dr. HF Tse (University of Hong Kong, Hong Kong) Prof. Dr. P Feijter (Erasmus MC, Rotterdam, The Netherlands)
TABLE OF CONTENTS
General introduction and outline of thesis 9
PART I Advanced clinical application of cardiac computed tomography
Chapter 1 Age- and gender-specific differences in the prognostic value of CT coronary angiography.
Yiu KH, de Graaf FR, Schuijf JD, van Werkhoven JM, Marsan NA, Veltman CE, de Roos A, Pazhenkottil A, Kroft LJ, Boersma E, Herzog B, Leung M, Maffei E, Leung DY, Kaufmann PA, Cademartiri F, Bax JJ, Jukema JW. Heart. 2012;98(3):232-7.
19
Chapter 2 Different value of coronary calcium score to predict obstructive coronary artery disease in patients with and without moderate chronic kidney disease.
Yiu KH, de Graaf FR, van Velzen JE, Marsan NA, Roos CJ, de Bie MK, Tse HF, van der Wall E, Schalij MJ, Bax JJ, Schuijf JD, Jukema JW. Neth Heart J. 2013;21(7-8):347- 53
29
Chapter 3 Prognostic value of renal dysfunction for the prediction of outcome versus results of computed tomographic coronary angiography
Yiu KH, de Graaf FR, Schuijf JD, van Werkhoven JM, van Velzen JE, Boogers MJ, Roos CJ, de Bie MK, Pazhenkottil A, Kroft LJ, Boersma E, Herzog B, de Roos A, Kaufmann PA, Bax JJ, Jukema JW. Am J Cardiol. 2011;108(7):968-72.
39
Chapter 4 Influence of left ventricular geometry and function on aortic annular dimensions as assessed with multi-detector row computed tomography: implications for transcatheter aortic valve implantation.
Ng AC, Yiu KH, Ewe SH, van der Kley F, Bertini M, de Weger A, de Roos A, Leung DY, Schuijf JD, Schalij MJ, Bax JJ, Delgado V. Eur Heart J. 2011;32(22):2806-13
47
PART II Advanced clinical application of novel echocardiographic modalities
Chapter 5 Myocardial structural alteration and systolic dysfunction in preclinical hypertrophic cardiomyopathy mutation carriers.
Yiu KH, Atsma DE, Delgado V, Ng AC, Witkowski TG, Ewe SH, Auger D, Holman ER, van Mil AM, Breuning MH, Tse HF, Bax JJ, Schalij MJ, Marsan NA. PLoS One.
2012;7(5):e36115
61
Chapter 6 Increased myocardial fibrosis and left ventricular dysfunction in Cushing's syndrome.
Yiu KH, Marsan NA, Delgado V, Biermasz NR, Holman ER, Smit JW, Feelders RA, Bax JJ, Pereira AM. Eur J Endocrinol. 2012;166(1):27-34
75
Chapter 7 Left ventricular dysfunction assessed by speckle-tracking strain analysis in patients with systemic sclerosis: relationship to functional capacity and ventricular arrhythmias.
Yiu KH, Schouffoer AA, Marsan NA, Ninaber MK, Stolk J, Vlieland TV, Scherptong RW, Delgado V, Holman ER, Tse HF, Huizinga TW, Bax JJ, Schuerwegh AJ. Arthritis Rheum. 2011;63(12):3969-78.
87
Chapter 8 Relationship between right ventricular function, pulmonary fibrosis and pulmonary pressures in patients with systemic sclerosis.
Yiu KH, Ninaber MK, Kroft L, Schouffoer AA, Stolk J, Vlieland TV, Delgado V, Tse HF, Bax JJ, Holman ER, Huizinga TW, Schuerwegh AJ, Marsan NA. Rheumatology (Oxford) 2016 ;55(3):504-12
101
Summary and Conclusions 115
Samenvatting en Conclusies 119
List of publications 125
Acknowledgements 135
Curriculum Vitae 137
To my father, Dr. Sing-Nam Yiu