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University of Groningen Iron Deficiency and Erythropoietin Excess: Two Sides of the Same Coin? Eisenga, Michele Freerk

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University of Groningen

Iron Deficiency and Erythropoietin Excess: Two Sides of the Same Coin?

Eisenga, Michele Freerk

DOI:

10.33612/diss.98865528

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Eisenga, M. F. (2019). Iron Deficiency and Erythropoietin Excess: Two Sides of the Same Coin? studies in patients with chronic kidney disease and in the general population. Rijksuniversiteit Groningen.

https://doi.org/10.33612/diss.98865528

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Propositions Belonging to PhD thesis

Iron Deficiency and Erythropoietin Excess:

Two Sides of the Same Coin?

By M.F. Eisenga

1. The association of iron deficiency with an increased risk of mortality in renal trans-plant recipients is independent of the presence of anemia. This thesis

2. The increased risk of mortality related to iron deficiency in renal transplant re-cipients might be due to increased levels of total fibroblast growth factor 23. This thesis

3. Transferrin saturation rather than ferritin level defines best the risk related to iron deficiency in chronic inflammatory states such as chronic kidney disease. This thesis

4. Previously identified adverse effects of administration of erythropoietin to patients with chronic kidney disease may, at least in part, be the consequence of upregulated production and concomitantly increased cleavage of fibroblast growth factor 23. This thesis

5. Both iron deficiency and erythropoietin excess are associated with increased levels of total fibroblast growth factor 23 in the general population. This thesis 6. Contrary to common belief, smoking as form of secondary erythrocytosis presents

with lower rather than higher erythropoietin levels. This thesis 7. Strike while the iron is hot. Geoffrey Chaucer

8. The only way to do great work is to love what you do. Steve Jobs

9. There are those who look at things the way they are, and ask why… I dream of things that never were, and ask why not. Robert Kennedy

10. Segui il tuo corso e lascia dir le genti. Dante Alighieri, La Divina Commedia 11. Life is a combination of magic and pasta. Federico Fellini

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