University of Groningen
Iron Deficiency and Erythropoietin Excess: Two Sides of the Same Coin?
Eisenga, Michele Freerk
DOI:
10.33612/diss.98865528
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Publication date: 2019
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Eisenga, M. F. (2019). Iron Deficiency and Erythropoietin Excess: Two Sides of the Same Coin? studies in patients with chronic kidney disease and in the general population. Rijksuniversiteit Groningen.
https://doi.org/10.33612/diss.98865528
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Propositions Belonging to PhD thesis
Iron Deficiency and Erythropoietin Excess:
Two Sides of the Same Coin?
By M.F. Eisenga
1. The association of iron deficiency with an increased risk of mortality in renal trans-plant recipients is independent of the presence of anemia. This thesis
2. The increased risk of mortality related to iron deficiency in renal transplant re-cipients might be due to increased levels of total fibroblast growth factor 23. This thesis
3. Transferrin saturation rather than ferritin level defines best the risk related to iron deficiency in chronic inflammatory states such as chronic kidney disease. This thesis
4. Previously identified adverse effects of administration of erythropoietin to patients with chronic kidney disease may, at least in part, be the consequence of upregulated production and concomitantly increased cleavage of fibroblast growth factor 23. This thesis
5. Both iron deficiency and erythropoietin excess are associated with increased levels of total fibroblast growth factor 23 in the general population. This thesis 6. Contrary to common belief, smoking as form of secondary erythrocytosis presents
with lower rather than higher erythropoietin levels. This thesis 7. Strike while the iron is hot. Geoffrey Chaucer
8. The only way to do great work is to love what you do. Steve Jobs
9. There are those who look at things the way they are, and ask why… I dream of things that never were, and ask why not. Robert Kennedy
10. Segui il tuo corso e lascia dir le genti. Dante Alighieri, La Divina Commedia 11. Life is a combination of magic and pasta. Federico Fellini