University of Groningen
Neuroinflammation as common denominator in heart failure associated mental dysfunction
Gouweleeuw, Leonie
DOI:
10.33612/diss.122192415
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Publication date:
2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Gouweleeuw, L. (2020). Neuroinflammation as common denominator in heart failure associated mental
dysfunction: Studies in animal models. University of Groningen. https://doi.org/10.33612/diss.122192415
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153 Curriculum Vitae
Curriculum Vitae
Leonie Gouweleeuw was born on the 22nd of October 1986 in The Hague, The Netherlands.
She completed high school at the Maerlant Lyceum in The Hague, in 2004. She then went on to study Biomedical Sciences in Leiden and finished her Bachelor in 2007 and her Master in 2009. She gained experience in practical research skills during her three internships at the departments of Molecular Cell Biology, Paediatrics and Medical Microbiology.
After her graduation in 2009, she decided it was time for a change of scenery and moved to Groningen to start her PhD at the department of Experimental Cardiology at the University Medical Centre Groningen in January 2010. When this project was stopped in 2012, she moved on to the department of Molecular Neurobiology, where she was supervised by Dr. Regien Schoemaker and Prof. dr. Ulrich Eisel. The experiments on heart failure associated neuroinflammation and mental dysfunction eventually culminated in this dissertation. In 2015, she also took on a project in collaboration with the Dutch institute for health and environment (RIVM) to test a possible vaccine in a mouse model of Alzheimers’ disease, whilst continuing data analysis on her PhD project.
Since 2017 Leonie Gouweleeuw works as a laboratory manager at the department of Microscopy Instruments and Techniques (MInT) at the Delft University of Technology.
154
List of publications
List of publications
Evidence for Neuroinflammation after Myocardial Infarction in a Mouse Model.
Gouweleeuw L, Pol C, Simonides WS, de Kleijn DPV, Schoemaker RG. Heart Mind 2017,
1(4):134-140.
Differences in the association between behavior and neutrophil gelatinase-associated lipocalin in male and female rats after coronary artery ligation.
Gouweleeuw L, Hovens IB, Liu H, Naudé PJ, Schoemaker RG. Physiol Behav. 2016 Sep
1;163:7-16.
Neutrophil gelatinase-associated lipocalin and microglial activity are associated with distinct postoperative behavioral changes in rats.
Gouweleeuw L, Hovens IB, van Leeuwen BL, Schoemaker RG. Behav Brain Res. 2016 Nov
16. pii: S0166-4328(16)30627-1.
The role of neutrophil gelatinase associated lipocalin (NGAL) as biological constituent linking depression and cardiovascular disease.
Gouweleeuw L, Naudé PJ, Rots M, DeJongste MJ, Eisel UL, Schoemaker RG. Brain Behav
Immun. 2015 May;46:23-32.
NGAL and other markers of inflammation as competitive or complementary markers for depressive symptom dimensions in heart failure.
Naudé PJ, Mommersteeg PM, Gouweleeuw L, Eisel UL, Denollet J, Westerhuis LW,
Schoemaker RG. World J Biol Psychiatry. 2015 Oct;16(7):536-41.
Neutrophil Gelatinase-Associated Lipocalin and depression in patients with chronic heart failure. Naudé PJ, Mommersteeg PM, Zijlstra WP, Gouweleeuw L, Kupper N, Eisel UL, Kop
WJ, Schoemaker RG. Brain Behav Immun. 2014 May;38:59-65.
Cardiac gene expression profiling - the quest for an atrium-specific biomarker.
Maass AH, De Jong AM, Smit MD, Gouweleeuw L, de Boer RA, Van Gilst WH, Van Gelder
IC. Neth Heart J. 2010 Dec;18(12):610-4.
