University of Groningen
Molecular insights into viral respiratory infections
Cong, Ying-Ying
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Publication date: 2019
Link to publication in University of Groningen/UMCG research database
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Cong, Y-Y. (2019). Molecular insights into viral respiratory infections. University of Groningen.
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PROPOSITIONS
Molecular insights into viral respiratory infections
Yingying Cong
1. Nidovirales induce membrane rearrangements including autophagosome formation in host cells. (this thesis)
2. β-CoV N proteins constitutively assemble into oligomers through a process that does not require binding to genomic RNA. (this thesis)
3. MHV N protein associates with RTCs through binding to nsp3 in a gRNA-independent manner, but N-RTC binding plays a stimulatory role in viral RNA transcription. (this thesis)
4. IAV triggers an autophagic response in host cells, but an intact ATG machinery is not required for the viral life cycle. (this thesis)
5. LC3 protein subfamily are recruited to vRNPs and play a crucial role in IAV infection though an autophagy-independent mechanism. (this thesis)
6. Anyone who has never made a mistake has never tried anything new. (Albert Einstein)
7. Fantasy is the poet’s wings, hypothesis is the ladder of science. (Johann Wolfgang von Goethe)
8. The flower that blooms in adversity is the most rare and beautiful of all.
