University of Groningen
Methodological aspects and standardization of PET radiomics studies
Pfaehler, Elisabeth
DOI:
10.33612/diss.149306583
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Publication date: 2021
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Pfaehler, E. (2021). Methodological aspects and standardization of PET radiomics studies. University of Groningen. https://doi.org/10.33612/diss.149306583
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Propositions
1. A standardization of each step in the radiomics pipeline is essential for the clinical implementation of PET radiomic features. (this thesis, Chapter 2-5)
2. Radiomic studies should be described in a way that each step can be easily reproduced by other research groups. (this thesis, Chapter 2)
3. Results of radiomic studies should be regarded with caution. (this thesis, Chapter 2,6) 4. Before the implementation of radiomics in the clinic, a large scale validation involving
multiple centers and PET scanners needs to be performed. (this thesis, Chapter 4-6)
5. Each segmentation method used for tumors in PET images has some limitations. (this thesis Chapter 7-9)
6. For the determination of treatment response, the repeatability of a segmentation method is essential. (this thesis, Chapter 8 and 9).
7. With four parameters I can fit an elephant, and with five I can make him wiggle his trunk. John von Neumann
8. And whatever we wish to find, we should (once found) regard with particular mistrust. Bertolt Brecht – Life of Galilei
9. There is nothing more wonderful than being a scientist, nowhere I would rather be than in my lab, staining up my clothes and getting paid to play.