Exploring betapapillomavirus infections and their association with cutaneous squamous-cell carcinoma
Plasmeijer, E.L.
Citation
Plasmeijer, E. L. (2010, October 26). Exploring betapapillomavirus infections and their association with cutaneous squamous-cell carcinoma. Retrieved from https://hdl.handle.net/1887/16071
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/16071
Note: To cite this publication please use the final published version (if
applicable).
Exploring
bEtapapillomavirus infEctions and thEir
association with cutanEous
squamous-cEll carcinoma
dEvElopmEnt
Colophon
Elsemieke Iebeliene Plasmeijer
Exploring betapapillomavirus infections and their association with cutaneous squamous- cell carcinoma development
Thesis, Leiden University, Leiden, The Netherlands
Cover image: Uluru 2008
Layout and printing: Optima Grafische Communicatie, Rotterdam, The Netherlands ISBN: 978-90-8559-066-8
©Elsemieke Plasmeijer, 2010
All rights reserved. No part of this book may be reproduced, stored or transmitted in any way without prior permission from the author.
Exploring betapapillomavir us infections and their association with cutaneous squamous-cell
carcinoma development
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van de Rector Magnificus prof.mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties te verdedigen op dinsdag 26 oktober 2010
klokke 15.00 uur door
Elsemieke Iebeliene Plasmeijer geboren te Almelo
in 1979
promotiecommissie
Promotores: Prof.Dr. A.C.M. Kroes
Prof.Dr. A.C. Green (University of Queensland, Brisbane, Australia) Copromotor: Dr. M.C.W. Feltkamp
Overige leden: Prof.Dr. J.A. Bruijn Prof.Dr. J. Vandenbroucke Prof.Dr. R. Willemze
Dr. W.G.V. Quint (DDL Diagnostic Laboratory, Voorburg, The Nether- lands)
Als je goed om je heen kijkt zie je dat alles gekleurd is -K. Schippers
Voor papa (1940-2002)
contEnts
Chapter 1 General introduction 9
Chapter 2 Transmission of betapapillomaviruses between domestic partners in an Australian community
27
Chapter 3 Betapapillomavirus infection profiles in tissue sets from cutaneous squamous cell-carcinoma patients
37
Chapter 4 Lack of association between the presence and persistence of betapapillomavirus DNA in eyebrow hairs and betapapillomavirus L1 antibodies in serum
53
Chapter 5 Persistence of betapapillomavirus infections as a risk factor for actinic keratoses, precur- sor to cutaneous squamous-cell carcinoma
71
Chapter 6 The association between cutaneous squamous cell carcinoma and betapapil- lomavirus seropositivity: a cohort study
89
Chapter 7 General discussion 105
Samenvatting 121
Publications 127
Authors and affiliations 131
Curriculum vitae 135
Dankwoord - Acknowledgements 139
