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Microparticles: mediators of cellular and environmental homeostasis

Böing, A.N.

Publication date

2011

Link to publication

Citation for published version (APA):

Böing, A. N. (2011). Microparticles: mediators of cellular and environmental homeostasis.

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STELLINGEN BEHORENDE BIJ HET PROEFSCHRIFT

‘Microparticles, mediators of cellular and environmental homeostasis’

1. Weefselfactor op micropartikels is niet altijd stollingsactief. (dit proefschrift) 2. Het afsnoeren van micropartikels bevordert de cellulaire overleving. (dit

proefschrift)

3. De stollingsactiviteit van weefselfactor is niet afhankelijk van de associatie met “raft” domeinen in membranen. (dit proefschrift)

4. De aanwezigheid van caspase-3 resulteert niet alleen in “membrane blebbing” maar ook in het afsnoeren van micropartikels. (dit proefschrift)

5. Of veneuze trombose wordt veroorzaakt door weefselfactor op micropartikels welke afkomstig zijn van de tumor is niet bewezen. (J.I. Zwicker et al. Clinical

Cancer Research 2009;15:6830-6840)

6. De beschreven aanwezigheid van micropartikels van bloedplaatjes in het synoviaal vocht bij patiënten met reumatoïde artritis is een artefact veroorzaakt door het gebruikte antilichaam. (E. Boilard et al. Science 2010;327:580-583)

7. Detectie van alle cellulaire “vesicles” in lichaamsvloeistoffen vereist het ontwikkelen van gevoeligere methoden (E. van der Pol et al. Journal of

Thrombosis and Haemostasis 2010;8:2596-2607)

8. Een kenniseconomie zal niet worden bereikt door te blijven bezuinigen op onderwijsen de eis van een “masters” titel voor docenten is geen garantie voor kwalitatief beter onderwijs.

9. Promoveren is leren omgaan met tegenslagen. 10. Duidelijk communiceren komt de resultaten ten goede.

11. Het gepromoveerd zijn is geen garantie voor het kunnen bedienen van een “multifunctional”.

12. Do you see, Pooh? Do you see, Piglet? Brains First and then hard work. (A.A.

Milne)

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