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University of Groningen Neuroinflammation as common denominator in heart failure associated mental dysfunction Gouweleeuw, Leonie

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University of Groningen

Neuroinflammation as common denominator in heart failure associated mental dysfunction

Gouweleeuw, Leonie

DOI:

10.33612/diss.122192415

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Gouweleeuw, L. (2020). Neuroinflammation as common denominator in heart failure associated mental dysfunction: Studies in animal models. University of Groningen. https://doi.org/10.33612/diss.122192415

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Stellingen 1. NGAL concentraties zijn een weerspiegeling van fysieke schade, zoals bij een hartinfarct 2. Vrouwtjes ratten reageren anders op een hartinfarct dan mannetjes ratten 3. Het risico op mentale dysfunctie na hartinfarct is niet alleen afhankelijk van de ernst van het infarct 4. Een ontstekingsreactie is een fysiologische respons op een hartinfarct, die een belangrijke functie heeft 5. Hart- en vaatziektes kunnen leiden tot ontstekingsreacties in de hersenen, welke geassocieerd kunnen worden met gedragsveranderingen in ratten 6. Er zijn serieuze uitdagingen in het vertalen van dierlijke gedragingen naar menselijk emoties 7. De tijd die nodig is om een proefschrift af te ronden stijgt significant met elk kind dat je in de tussentijd krijgt 8. Het veelvuldig uitvoeren van gedragstesten kan leiden tot mentale dysfunctie in PhD studenten 9. If we knew what we were doing, it would not be called research – Albert Einstein 10. Do or do not, there is no try - Yoda

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