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University of Groningen The roles of MYO5B in epithelial cells and the intestine Leng, Changsen

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University of Groningen

The roles of MYO5B in epithelial cells and the intestine Leng, Changsen

DOI:

10.33612/diss.127906021

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Leng, C. (2020). The roles of MYO5B in epithelial cells and the intestine: A focus on microvillus inclusion disease. University of Groningen. https://doi.org/10.33612/diss.127906021

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Stellingen

Behorende bij het proefschrift

by

Changsen Leng

1. Recycling endosomes control late endo-lysosomal homeostasis. (this thesis) 2. Lysosomes are more susceptible to oxidative damage compared to other

organelles because they contain more redox-active iron and fewer antioxidants. (this thesis and Yu et al., Free Radic Biol Med 2003)

3. Cells do not actively monitor endosome size during mitosis. (this thesis)

4. Oxidative lysosomal damage and resultant death of enterocytes is part of microvillus inclusion disease (MVID) pathogenesis. (this thesis)

5. Both symmetry and asymmetry serve as highly aesthetic sources of beauty (Zaidel et al., Symmetry 2010;2).

6. Lysosomes have numerous survival functions but also act as “suicide bags” in the cells. (this thesis and Turk et al., J Biol Chem 2009)

7. Chance favors the prepared mind. (机会青睐于有准备的人)

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