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University of Groningen

New insights in the disinfection of the root canal system using different research models

Pereira, Thais

DOI:

10.33612/diss.119787964

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Pereira, T. (2020). New insights in the disinfection of the root canal system using different research models. University of Groningen. https://doi.org/10.33612/diss.119787964

Copyright

Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).

Take-down policy

If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.

Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

(2)

University of Groningen

New insights in the disinfection of the root canal system using different research models

Pereira, Thais

DOI:

10.33612/diss.119787964

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Pereira, T. (2020). New insights in the disinfection of the root canal system using different research models. [Groningen]: University of Groningen. https://doi.org/10.33612/diss.119787964

Copyright

Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).

Take-down policy

If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.

Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

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1

New insights into the

disinfection of the root canal

system using different research

models

Thais Cristina Pereira

141761_Pereira_BNW.indd 1

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New insights into the disinfection of the root canal system using different research models.

University Medical Center Groningen, University of Groningen Groningen, The Netherlands

Copyright © 2020 by Thais Cristina Pereira Cover:

Printed by Gildeprint

ISBN (printed version): 978-94-034-2352-4

ISBN (electronic version): 978-94-034-2351-7

New insights into the disinfection of the root

canal system using different research models

PhD thesis

to obtain the degree of PhD of the University of Groningen

on the authority of the Rector Magnificus Prof. C. Wijmenga

and in accordance with the decision by the College of Deans

and

to obtain the degree of PhD at the University of São Paulo

on the authority of the Rector Prof. Vahan Agopyan

and in accordance with

the decision by Pro-Rectory of Post-Graduation

Double PhD degree

This thesis will be defended in public on Wednesday 25 March 2019 at 14:30 hours

by

Thais Cristina Pereira

born on 25 May 1989, in Promissão, Brazil

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3

New insights into the disinfection of the root

canal system using different research models

PhD thesis

to obtain the degree of PhD of the University of Groningen

on the authority of the Rector Magnificus Prof. C. Wijmenga

and in accordance with the decision by the College of Deans

and

to obtain the degree of PhD at the University of São Paulo

on the authority of the Rector Prof. Vahan Agopyan

and in accordance with

the decision by Pro-Rectory of Post-Graduation

Double PhD degree

This thesis will be defended in public on Wednesday 1 July 2020 at 14:30 hours

by

Thais Cristina Pereira

born on 25 May 1989, in Promissão, Brazil

141761_Pereira_BNW.indd 3

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Supervisors

Prof. L.W.M. van der Sluis

Co-supervisors

Prof. F.B. de Andrade Dr. P.K. Sharma Dr. W.J. van der Meer

Assessment committee

Prof. M. Georgopoulou Prof. M.T. Arias Moliz Prof. C.F. dos Santos Prof. Y. Ren

To the memory of my grandmother Célia who always encouraged me to be a

writer, To my mommy and daddy, sisters and brother, To my husband, To

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5

To the memory of my grandmother Célia who always encouraged me to be a

writer, To my mommy and daddy, sisters and brother, To my husband, To

everybody that I love.

141761_Pereira_BNW.indd 5

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Paranymphs

Víctor Amador Garcías Real Mariana Maciel Batista Broges

Table of Contents

Chapter 1 General introduction and aim of this thesis 9

Chapter 2 Intratubular decontamination ability and

physico-chemical properties of calcium hydroxide pastes

Thais Cristina Pereira; Layla Reginna da Silva Munhoz Vasconcelos; Márcia Sirlene Zardin Graeff; Maria Cristina Marcucci Ribeiro; Marco Antonio Hungaro Duarte; Flaviana Bombarda de Andrade

Clin Oral Investig, 2018, 10.1007/s00784-018-2549-0

37

Chapter 3 Antibacterial properties of silver nanoparticles as a root

canal irrigant against Enterococcus faecalis biofilm and infected dentinal tubules

Clarissa Teles Rodrigues; Flaviana Bombarda de Andrade; Layla Reginna da Silva Munhoz Vasconcelos; Raquel Zanin Midena; Thais Cristina Pereira; Milton Carlos Kuga; Marco Antonio Hungaro Duarte; Norberti Bernardineli

Int Endod J, 2018, 10.1111/iej.12904

63

Chapter 4 Biofilm removal from an artificial isthmus and lateral

canal during syringe irrigation at various flow rates: a combined experimental and Computational Fluid Dynamics approach

Thais Cristina Pereira; Christos Boutsioukis; René Dijkstra; Xenos Petridis; Michel Versluis; Flaviana Bombarda de Andrade; Wicher Jurjen van der Meer; Prashant Sharma; Lucas Wilhelmus Maria van der Sluis; Marcus Vinícius Reis Só

Submitted to International Endodontic Journal

87

Chapter 5 Chemical and mechanical influence of root canal

irrigation on biofilm removal from lateral morphological 111

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7

Table of Contents

Chapter 1 General introduction and aim of this thesis 9

Chapter 2 Intratubular decontamination ability and

physico-chemical properties of calcium hydroxide pastes

Thais Cristina Pereira; Layla Reginna da Silva Munhoz Vasconcelos; Márcia Sirlene Zardin Graeff; Maria Cristina Marcucci Ribeiro; Marco Antonio Hungaro Duarte; Flaviana Bombarda de Andrade

Clin Oral Investig, 2018, 10.1007/s00784-018-2549-0

37

Chapter 3 Antibacterial properties of silver nanoparticles as a root

canal irrigant against Enterococcus faecalis biofilm and infected dentinal tubules

Clarissa Teles Rodrigues; Flaviana Bombarda de Andrade; Layla Reginna da Silva Munhoz Vasconcelos; Raquel Zanin Midena; Thais Cristina Pereira; Milton Carlos Kuga; Marco Antonio Hungaro Duarte; Norberti Bernardineli

Int Endod J, 2018, 10.1111/iej.12904

63

Chapter 4 Biofilm removal from an artificial isthmus and lateral

canal during syringe irrigation at various flow rates: a combined experimental and Computational Fluid Dynamics approach

Thais Cristina Pereira; Christos Boutsioukis; René Dijkstra; Xenos Petridis; Michel Versluis; Flaviana Bombarda de Andrade; Wicher Jurjen van der Meer; Prashant Sharma; Lucas Wilhelmus Maria van der Sluis; Marcus Vinícius Reis Só

Submitted to International Endodontic Journal

87

Chapter 5 Chemical and mechanical influence of root canal

irrigation on biofilm removal from lateral morphological features of the root canal and dentinal tubules.

111

141761_Pereira_BNW.indd 7

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Thais Cristina Pereira; René Dijkstra; Xenos Petridis; Prashant Sharma; Wicher Jurjen van der Meer, Lucas Wilhelmus Maria van der Sluis; Flaviana Bombarda de Andrade

Submitted to International Endodontic Journal

Chapter 6

Chapter 7

The influence of time and irrigant refreshment on biofilm removal from lateral morphological features.

Thais Cristina Pereira; René Dijkstra; Xenos Petridis; Wicher Jurjen van der Meer; Prashant Sharma; Flaviana Bombarda de Andrade; Lucas Wilhelmus Maria van der Sluis.

Accepted for publication in International Endodontic Journal General discussion 153 176 Summary Samenvatting Sumário Acknowledgements

Curriculum Vitae and Publications

193 198 202 206 213 176 195 200 204 209 216

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